Evidence map›Paper›PMID 28629380›Full record

ArticleBMC cancer2017

Retinal and vitreous metastases from hepatocholangiocarcinoma.

Anna Praidou, Sarita Jacob, Luciane Irion, Ramesh Sivaraj, Carl Groenewald, Sarah E Coupland, Heinrich Heimann

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Metastatic papillary renal cell carcinoma to the retina and vitreous.American journal of ophthalmology case reports · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. [Intraocular metastases].Der Pathologe · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anna PraidouOcular Oncology Service, St Paul's Eye Unit, Royal Liverpool University Hospital, L7 8XP, Liverpool, UK. praidou2003@yahoo.co.uk.ORCID http://orcid.org/0000-0001-6297-049X
Sarita JacobDepartment of Ophthalmology, Heart of England NHS Foundation Trust, Birmingham, UK.
Luciane IrionDepartment of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Ramesh SivarajDepartment of Ophthalmology, Heart of England NHS Foundation Trust, Birmingham, UK.
Carl GroenewaldOcular Oncology Service, St Paul's Eye Unit, Royal Liverpool University Hospital, L7 8XP, Liverpool, UK.
Sarah E CouplandDepartment of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Heinrich HeimannOcular Oncology Service, St Paul's Eye Unit, Royal Liverpool University Hospital, L7 8XP, Liverpool, UK.
University of Liverpool · GBHeart of England NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo report a case of metastatic hepatocholangiocarcinoma to the vitreous and retina. CASE PRESENTATION: A 70-year-old male, who was recently diagnosed with hepatocholangiocarcinoma, was complaining of floaters in his right eye over the past 5 months and was referred to the Liverpool Ocular Oncology Centre. On presentation, his visual acuity in the right eye was 6/24. Fundus exam revealed a whitish, unilateral, full-thickness retinal lesion at the inferotemporal arcade of his right eye, with vitreous infiltration and subretinal fluid. The patient underwent 25G pars plana vitrectomy with biopsy, resection of the lesion and intravitreal bevacizumab injection. Histopathology testing of the surgical specimens confirmed the diagnosis of metastatic carcinoma to the eye. Two months postoperatively his visual acuity had improved to 6/7.5 and there was no sign of active disease in his right eye, while 9 months postoperatively his visual acuity decreased to 6/9.5 due to developing nuclear sclerotic cataract in his right eye.

conclusionThe current report presents the first case of a hepatocholangiocarcinoma metastasis to the vitreous and retina.

Indexed as

AgedAntineoplastic Combined Chemotherapy ProtocolsBile Duct NeoplasmsBiopsyCholangiocarcinomaFatal OutcomeHumansImmunohistochemistryMaleRetinal NeoplasmsTomography, X-Ray ComputedVitrectomyVitreous BodyEyeHepatocholangiocarcinomaMetastasesMetastasisRetinaVitreous

Identifiers

PMID28629380
PMCPMC5477246
OpenAlexW2655748712

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.