Evidence map›Paper›PMID 28629161›Full record

ReviewMolecules (Basel, Switzerland)2017

Cancer Chemoprevention by Resveratrol: The p53 Tumor Suppressor Protein as a Promising Molecular Target.

Danielly C Ferraz da Costa, Eliane Fialho, Jerson L Silva

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Phytochemicals Target Multiple Metabolic Pathways in Cancer.Antioxidants (Basel, Switzerland) · 2023
    Review
  8. Review
  9. Research in pharmaceutical sciences · 2022
    Article
  10. Review
  11. Article
  12. Review
  13. Green Tea (Foods (Basel, Switzerland) · 2021
    Article
  14. Review
  15. Review
  16. Review
  17. p53 EnhancesInternational journal of molecular sciences · 2020
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Danielly C Ferraz da CostaInstituto de Nutrição, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 20550-013, Brazil. danielly.costa@uerj.br.
Eliane FialhoInstituto de Nutrição Josué de Castro, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil. fialho@nutricao.ufrj.br.
Jerson L SilvaInstituto de Bioquímica Médica Leopoldo de Meis & Instituto Nacional de Ciência e Tecnologia de Biologia Estrutural e Bioimagem, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21941-902, Brazil. fialho@ufrj.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing epidemiological and experimental evidence has demonstrated an inverse relationship between the consumption of plant foods and the incidence of chronic diseases, including cancer. Microcomponents that are naturally present in such foods, especially polyphenols, are responsible for the benefits to human health. Resveratrol is a diet-derived cancer chemopreventive agent with high therapeutic potential, as demonstrated by different authors. The aim of this review is to collect and present recent evidence from the literature regarding resveratrol and its effects on cancer prevention, molecular signaling (especially regarding the involvement of p53 protein), and therapeutic perspectives with an emphasis on clinical trial results to date.

Indexed as

ChemopreventionAnimalsAntineoplastic Agents, PhytogenicBiological AvailabilityBiomarkers, TumorClinical Trials as TopicGene Expression Regulation, NeoplasticHumansNeoplasmsOutcome Assessment, Health CareResveratrolSignal TransductionStilbenesTumor Suppressor Protein p53Antineoplastic Agents, PhytogenicBiomarkers, TumorResveratrolStilbenesTumor Suppressor Protein p53cancerclinical trialsp53resveratrolsignal transduction

Identifiers

PMID28629161
PMCPMC6152653

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.