Evidence map›Paper›PMID 28629129›Full record

ReviewNutrients2017

Dietary Management of Skin Health: The Role of Genistein.

Natasha Irrera, Gabriele Pizzino, Rosario D'Anna, Mario Vaccaro, Vincenzo Arcoraci, Francesco Squadrito, Domenica Altavilla, Alessandra Bitto

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 76 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. The Therapeutic Role of Genistein in Perimenopausal and Postmenopausal Women.The Journal of clinical and aesthetic dermatology · 2024
    Review
  9. Review
  10. Biosynthesis and Anticancer Activity of Genistein Glycoside Derivatives.Anti-cancer agents in medicinal chemistry · 2024
    Review
  11. Article
  12. Review
  13. Review
  14. Alpinumisoflavone against cancer pro-angiogenic targets: In silico, In vitro, and In ovo evaluation.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2022
    Article
  15. The Effects of Genistein at Different Concentrations onInternational journal of molecular sciences · 2022
    Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Natasha IrreraDepartment of Clinical and Experimental Medicine, University of Messina, Messina 98125, Italy. nirrera@unime.it.
Gabriele PizzinoDepartment of Clinical and Experimental Medicine, University of Messina, Messina 98125, Italy. cgpizzino@unime.it.
Rosario D'AnnaDepartment of Human Pathology, University of Messina, Messina 98125, Italy. rdanna@unime.it.
Mario VaccaroDepartment of Clinical and Experimental Medicine, University of Messina, Messina 98125, Italy. vaccaro@unime.it.
Vincenzo ArcoraciDepartment of Clinical and Experimental Medicine, University of Messina, Messina 98125, Italy. varcoraci@unime.it.
Francesco SquadritoDepartment of Clinical and Experimental Medicine, University of Messina, Messina 98125, Italy. fsquadrito@unime.it.
Domenica AltavillaDepartment of Biomedical Sciences, Dentistry and Morphological and Functional Images, University of Messina, Messina 98125, Italy. daltavilla@unime.it.
Alessandra BittoDepartment of Clinical and Experimental Medicine, University of Messina, Messina 98125, Italy. abitto@unime.it.
University of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In women, aging and declining estrogen levels are associated with several cutaneous changes, many of which can be reversed or improved by estrogen supplementation. Two estrogen receptors-α and β-have been cloned and found in various tissue types. Epidermal thinning, declining dermal collagen content, diminished skin moisture, decreased laxity, and impaired wound healing have been reported in postmenopausal women. Experimental and clinical studies in postmenopausal conditions indicate that estrogen deprivation is associated with dryness, atrophy, fine wrinkling, and poor wound healing. The isoflavone genistein binds to estrogen receptor β and has been reported to improve skin changes. This review article will focus on the effects of genistein on skin health.

Indexed as

PostmenopauseFemaleGenisteinHumansSkinSkin AgingGenisteinestrogen receptor betagenisteinskin

Identifiers

PMID28629129
PMCPMC5490601
OpenAlexW2626649577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.