Evidence map›Paper›PMID 28629124›Full record

ReviewMarine drugs2017

Microbial Diseases of Bivalve Mollusks: Infections, Immunology and Antimicrobial Defense.

Carla Zannella, Francesco Mosca, Francesca Mariani, Gianluigi Franci, Veronica Folliero, Marilena Galdiero, Pietro Giorgio Tiscar, Massimiliano Galdiero

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 198 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Prevalence and Intensity ofPathogens (Basel, Switzerland) · 2025
    Article
  8. Review
  9. Review
  10. The Role ofAnimals : an open access journal from MDPI · 2025
    Article
  11. Article
  12. Analyzing antibacterial potential of bellamyaFrontiers in pharmacology · 2025
    Article
  13. Deep learning for genomic selection of aquatic animals.Marine life science & technology · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Viral Diversity in Samples of Freshwater GastropodsInternational journal of molecular sciences · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Carla ZannellaDepartment of Experimental Medicine-University of Campania "Luigi Vanvitelli", Via Costantinopoli 16, 80138 Napoli, Italy. carlazannella88@gmail.com.
Francesco MoscaFaculty of Veterinary Medicine, University of Teramo, Piano d'Accio, 64100 Teramo, Italy. gianluigi.franci@unina2.it.
Francesca MarianiFaculty of Veterinary Medicine, University of Teramo, Piano d'Accio, 64100 Teramo, Italy. veronica.folliero@unina2.it.
Gianluigi FranciDepartment of Experimental Medicine-University of Campania "Luigi Vanvitelli", Via Costantinopoli 16, 80138 Napoli, Italy. marilena.galdiero@unina2.it.
Veronica FollieroDepartment of Experimental Medicine-University of Campania "Luigi Vanvitelli", Via Costantinopoli 16, 80138 Napoli, Italy. fmariani@unite.it.
Marilena GaldieroDepartment of Experimental Medicine-University of Campania "Luigi Vanvitelli", Via Costantinopoli 16, 80138 Napoli, Italy. pgtiscar@unite.it.
Pietro Giorgio TiscarFaculty of Veterinary Medicine, University of Teramo, Piano d'Accio, 64100 Teramo, Italy. pgtiscar@unite.it.
Massimiliano GaldieroDepartment of Experimental Medicine-University of Campania "Luigi Vanvitelli", Via Costantinopoli 16, 80138 Napoli, Italy. massimiliano.galdiero@cantab.net.
University of Campania "Luigi Vanvitelli" · ITUniversity of Teramo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A variety of bivalve mollusks (phylum Mollusca, class Bivalvia) constitute a prominent commodity in fisheries and aquacultures, but are also crucial in order to preserve our ecosystem's complexity and function. Bivalve mollusks, such as clams, mussels, oysters and scallops, are relevant bred species, and their global farming maintains a high incremental annual growth rate, representing a considerable proportion of the overall fishery activities. Bivalve mollusks are filter feeders; therefore by filtering a great quantity of water, they may bioaccumulate in their tissues a high number of microorganisms that can be considered infectious for humans and higher vertebrates. Moreover, since some pathogens are also able to infect bivalve mollusks, they are a threat for the entire mollusk farming industry. In consideration of the leading role in aquaculture and the growing financial importance of bivalve farming, much interest has been recently devoted to investigate the pathogenesis of infectious diseases of these mollusks in order to be prepared for public health emergencies and to avoid dreadful income losses. Several bacterial and viral pathogens will be described herein. Despite the minor complexity of the organization of the immune system of bivalves, compared to mammalian immune systems, a precise description of the different mechanisms that induce its activation and functioning is still missing. In the present review, a substantial consideration will be devoted in outlining the immune responses of bivalves and their repertoire of immune cells. Finally, we will focus on the description of antimicrobial peptides that have been identified and characterized in bivalve mollusks. Their structural and antimicrobial features are also of great interest for the biotechnology sector as antimicrobial templates to combat the increasing antibiotic-resistance of different pathogenic bacteria that plague the human population all over the world.

Indexed as

AnimalsAntimicrobial Cationic PeptidesBivalviaImmune SystemImmunity, InnateAntimicrobial Cationic Peptidesantimicrobial peptidesbivalve immune systemmarine bivalve mollusks

Identifiers

PMID28629124
PMCPMC5484132
OpenAlexW2626112736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.