Evidence map›Paper›PMID 28628853›Full record

ArticleThe International journal on drug policy2017

Willingness to pay for opioid agonist treatment among opioid dependent people who inject drugs in Ukraine.

Iuliia Makarenko, Alyona Mazhnaya, Ruthanne Marcus, Martha J Bojko, Lynn Madden, Sergii Filippovich, Sergii Dvoriak, Frederick L Altice

Abstract read
In one paragraph

Article in The International journal on drug policy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Iuliia MakarenkoICF Alliance for Public Health, Kyiv, Ukraine; Yale University School of Medicine, Section of Infectious Diseases, AIDS Program, New Haven, CT, USA. Electronic address: makarenko.j@gmail.com.
Alyona MazhnayaICF Alliance for Public Health, Kyiv, Ukraine.
Ruthanne MarcusYale University School of Medicine, Section of Infectious Diseases, AIDS Program, New Haven, CT, USA.
Martha J BojkoYale University School of Medicine, Section of Infectious Diseases, AIDS Program, New Haven, CT, USA.
Lynn MaddenYale University School of Medicine, Department of Psychiatry, New Haven, CT, USA; APT Foundation, New Haven, CT, USA.
Sergii FilippovichICF Alliance for Public Health, Kyiv, Ukraine.
Sergii DvoriakUkrainian Institute on Public Health Policy, Kyiv, Ukraine.
Frederick L AlticeYale University School of Medicine, Section of Infectious Diseases, AIDS Program, New Haven, CT, USA; Yale University School of Public Health, Division of Epidemiology of Microbial Diseases, New Haven, CT, USA.
Yale University · USAlliance for Public Health · UAUkrainian Institute of Public Health Policy · UA

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
Training in the Epidemiology of HPV/Cervical Neoplasia Among HIV+ WomenD43TW000233 · FIC · SUNY DOWNSTATE MEDICAL CENTER · PI DEHOVITZ, JACK A · 1993 to 2015
$10.1M
Prison Interventions and HIV Prevention CollaborationR01DA029910 · NIDA · YALE UNIVERSITY · PI FREDERICK LEWIS ALTICE · 2010 to 2026
$7.9M
Expanding Medication Assisted Therapy in Ukraine (ExMAT)R01DA033679 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2012 to 2021
$6.4M
Global Health Fellows and Scholars Research TrainingR25TW009338 · FIC · UNIVERSITY OF CALIFORNIA BERKELEY · PI BARRY, MICHELE, KO, ALBERT ICKSANG · 2012 to 2016
$5.2M
Enhancing Health Outcomes Among HIV+ Substance AbusersK24DA017072 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2003 to 2012
$1.5M
FIC NIH HHS D43 TW000233FIC NIH HHS D43 TW010540FIC NIH HHS R25 TW009338NCATS NIH HHS UL1 TR001863NIDA NIH HHS K24 DA017072NIDA NIH HHS R01 DA029910NIDA NIH HHS R01 DA033679
6 · The paper itself

Abstract

backgroundIn the context of decreasing external and limited Ukrainian governmental funding for opioid agonist treatments (OAT) for opioid dependent people who inject drugs in Ukraine, information on sustainable financial models is needed.

methodsData on 855 opioid dependent people who inject drugs (PWID) were drawn from a cross-sectional nationwide survey of 1613 PWID. They comprised 434 participants who were receiving OAT and 421 who were on OAT in the past or have never been on OAT and were interested in receiving the treatment. Multivariate logistic regression was used to examine factors associated with willingness-to-pay (WTP) for OAT, stratified by OAT experience. Variation in the price which respondents were willing to pay for OAT and its effect on their monthly income among PWID with different OAT experience were assessed as a continuous variable using one-way ANOVA and Kruskal-Wallis test.

resultsOverall, 378 (44%) expressed WTP for OAT. Factors independently associated with WTP differed by OAT experience. Among those using OAT, independent predictors of WTP included: city (Dnipro - aOR=1.9; 95%CI=1.1-4.8 and Lviv - (aOR=2.2; 95%CI=1.1-4.8) compared to those elsewhere in Ukraine), higher income (aOR=1.8; 95%CI=1.2-2.7) and receiving psychosocial counseling (aOR=1.8; 95%CI=1.2-2.7). Among those who had previously been on OAT, positive attitude towards OAT (aOR=1.3; 95%CI=1.1-1.6) and family support of OAT (aOR=2.5; 95%CI=1.1-5.7) were independently associated with WTP. Among PWID who had never been on OAT, being male (aOR=2.2; 95%CI=1.1-4.2), younger age (aOR=1.9; 95%CI=1.2-3.2), higher income (aOR=2.0; 95%CI=1.2-3.4) and previous unsuccessful attempts to enter OAT (aOR=2.3; 95%CI=1.1-4.7) were independently associated with WTP. PWID were willing to commit a large percentage of their monthly income for OAT, which, however, varied significantly based on OAT experience: current OAT: 37% of monthly income, previous OAT: 53%, and never OAT: 60% (p-value=0.0009).

conclusionsWTP for OAT was substantial among PWID in Ukraine, supporting the implementation of self-pay or co-payment programs. Such strategies, however, must remain affordable, provide better access to OAT, and consider specific needs of PWID.

Indexed as

Health Services AccessibilityMotivationAdultAge FactorsAnalgesics, OpioidAttitudeCross-Sectional StudiesFemaleHumansIncomeMaleOpioid-Related DisordersSex FactorsSocial SupportSubstance Abuse, IntravenousUkraineAnalgesics, OpioidBuprenorphineMethadoneOpioid agonist therapyUkraineWillingness to pay

Identifiers

PMID28628853
PMCPMC5533603
OpenAlexW2626238228

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.