Evidence map›Paper›PMID 28628638›Full record

ArticlePloS one2017

Temperature and concentration calibration of aqueous polyvinylpyrrolidone (PVP) solutions for isotropic diffusion MRI phantoms.

Friedrich Wagner, Frederik B Laun, Tristan A Kuder, Anna Mlynarska, Florian Maier, Jonas Faust, Kerstin Demberg, Linus Lindemann, Boris Rivkin, Armin M Nagel and 4 more

Abstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Friedrich WagnerMedical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Frederik B LaunMedical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Tristan A KuderMedical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Anna MlynarskaRadiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Florian MaierMedical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Jonas FaustMedical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Kerstin DembergMedical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Linus LindemannMedical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Boris RivkinMedical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Armin M NagelMedical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Mark E LaddMedical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Klaus Maier-HeinMedical and Biological Informatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Sebastian BickelhauptRadiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Michael BachMedical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To use the "apparent diffusion coefficient" (Dapp) as a quantitative imaging parameter, well-suited test fluids are essential. In this study, the previously proposed aqueous solutions of polyvinylpyrrolidone (PVP) were examined and temperature calibrations were obtained. For example, at a temperature of 20°C, Dapp ranged from 1.594 (95% CI: 1.593, 1.595) μm2/ms to 0.3326 (95% CI: 0. 3304, 0.3348) μm2/ms for PVP-concentrations ranging from 10% (w/w) to 50% (w/w) using K30 polymer lengths. The temperature dependence of Dapp was found to be so strong that a negligence seems not advisable. The temperature dependence is descriptively modelled by an exponential function exp(c2 (T - 20°C)) and the determined c2 values are reported, which can be used for temperature calibration. For example, we find the value 0.02952 K-1 for 30% (w/w) PVP-concentration and K30 polymer length. In general, aqueous PVP solutions were found to be suitable to produce easily applicable and reliable Dapp-phantoms.

Indexed as

Diffusion Magnetic Resonance ImagingCalibrationPhantoms, ImagingPolymersPovidoneSolutionsTemperaturePolymersPovidoneSolutions

Identifiers

PMID28628638
PMCPMC5476261

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.