ArticleAnnals of surgery2018
Open versus Laparoscopic Surgery for Advanced Low Rectal Cancer: A Large, Multicenter, Propensity Score Matched Cohort Study in Japan.
Article in Annals of surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
69 citing papers in PubMed, 4 syntheses or guidelines pooled it, 118 citations in OpenAlex.
- Effect of home-based exercise prehabilitation on postoperative outcomes in colorectal cancer surgery: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Laparoscopy is non-inferior to open surgery for rectal cancer: A systematic review and meta-analysis.Cancer medicine · 2024Pooled it
- Laparoscopic versus open surgery in obstructive colorectal cancer patients following stents placement: a comprehensive meta-analysis of cohort studies.Surgical endoscopy · 2024Pooled it
- Clinical efficacy of anastomotic reinforcement suture in preventing anastomotic leakage after rectal cancer surgery: a systematic review and meta-analysis.Langenbeck's archives of surgery · 2023Pooled it
- Comparative Oncologic Outcomes of Laparoscopic versus Open Surgery for Early-Onset Low Rectal Cancer: 3-Year Results From the LASRE Trial.World journal of surgery · 2026Trial
- Unveiling the impact of body mass index on surgical difficulty and oncological prognosis in low rectal cancer: post-hoc analysis of the LASRE trial.International journal of colorectal disease · 2025Trial
- Textbook outcome in low rectal cancer patients undergoing laparoscopic or open surgery: 3-year results from the multicentric LASRE Trial.International journal of colorectal disease · 2025Trial
- Impact of hospital volume on laparoscopic surgery for locally advanced rectal cancer: a subanalysis of the JSLCS multicenter observational study.Surgery today · 2026Article
- Dynamic changes in the aggregate index of systemic inflammation (ΔAISI) predict postoperative complications following ileostomy closure in rectal cancer patients.BMC surgery · 2026Article
- Impact of CRM-oriented specimen processing on lymph node retrieval: a prospective multicenter study evaluating the risk of a suboptimal lymph node yield in rectal cancer.Surgery today · 2026Article
- Endoscopic Full-Thickness Resection for Gastrointestinal Subepithelial and Epithelial Neoplasia: Current Status, Indications, and Technical and Oncological Challenges-A Multispecialty Perspective.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Review
- Laparoscopic surgery should be a viable option for T4 colon cancer: evidence from a propensity score matching analysis.Updates in surgery · 2026Observational
- Assessment of reinforcing sutures of double-stapling anastomosis with manual and powered circular staplers in Porcine models.Scientific reports · 2026Article
- Robotic surgery enhances patients' survival in rectal cancer: a propensity score-weighted multicenter cohort study.Surgical endoscopy · 2025Article
- Effect of Total Mesorectal Excision (TME) quality on 3-year overall survival in low rectal cancer based on the LASRE trial.Scientific reports · 2025Article
- Current surgical treatment strategies and ongoing issues for locally recurrent rectal cancer.Japanese journal of clinical oncology · 2025Review
- Patient-Reported Outcomes and Surgical Results of Hand-Sewn Versus Stapled Anastomosis for Lower Rectal Cancer Located 4-5 cm From the Anal Verge: A Subanalysis of the Ultimate Study.Annals of gastroenterological surgery · 2025Article
- Risk Factors for and Oncologic Impact of Anastomotic Leakage After Sphincter-Preserving Proctectomy for Mid/Low Rectal Cancer: A Multi-institutional Cohort Study in Japan.Annals of surgical oncology · 2025Article
- Short-term outcomes of intracorporeal anastomosis in laparoscopic colectomy for colon cancer: A nationwide, multi-institutional cohort study in Japan (ICAN study).Annals of gastroenterological surgery · 2025Article
- Efficacy of reinforcing sutures in preventing anastomotic leakage after surgery for rectal cancer: A systematic review and metaanalysis.World journal of gastrointestinal surgery · 2025Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLaparoscopic surgery for rectal cancer is widely performed all over the world and several randomized controlled trials have been reported. However, the usefulness of laparoscopic surgery compared with open surgery has not been demonstrated sufficiently, especially for the low rectal area.
objectiveThe aim of this study was to investigate the hypothesis that laparoscopic primary tumor resection is safe and effective when compared with the open approach for locally advanced low rectal cancer. PATIENTS AND
methodsData from patients with clinical stage II to III low rectal cancer below the peritoneal reflection were collected and analyzed. The operations were performed from 2010 to 2011. Short-term outcomes and long-term prognosis were analyzed with propensity score matching.
resultsOf 1608 cases collated from 69 institutes, 1500 cases were eligible for analysis. The cases were matched into 482 laparoscopic and 482 open cases. The mean height of the tumor from the anal verge was 4.6 cm. Preoperative treatment was performed in 35% of the patients. The conversion rate from laparoscopic to open surgery was 5.2%. Estimated blood loss during laparoscopic surgery was significantly less than that during open surgery (90 vs 625 mL, P < 0.001). Overall, the occurrence of complications after laparoscopic surgeries was less than that after open surgeries (30.3% vs 39.2%, P = 0.005). Three-year overall survival rates were 89.9% [95% confidence interval (95% CI) 86.7-92.4] and 90.4% (95% CI 87.4-92.8) in the laparoscopic and open groups, respectively, and no significant difference was seen between the 2 groups. No significant difference was observed in recurrence-free survival (RFS) between the 2 groups (3-year RFS: 70.9%, 68.4 to 74.2 vs 71.8%, 67.5 to 75.7).
conclusionLaparoscopic surgery could be considered as a treatment option for advanced, low rectal cancer below the peritoneal reflection, based on the short-term and long-term results of this large cohort study (UMIN-ID: UMIN000013919).
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