Evidence map›Paper›PMID 28628553›Full record

ArticleJournal of neurologic physical therapy : JNPT2017

Single-Case Design, Analysis, and Quality Assessment for Intervention Research.

Michele A Lobo, Mariola Moeyaert, Andrea Baraldi Cunha, Iryna Babik

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurologic physical therapy : JNPT, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 76 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05367947 nacompletednot on this mapstarted 2023, after this paper: background citation

Investigation of In-phase Bilateral Exercise Effects on Corticospinal Plasticity in Relapsing Remitting Multiple Sclerosis: a Registered Report Single-case Concurrent Multiple Baseline Design Across Five Subjects

TypeinterventionalSponsorCyprus University of TechnologyRan2023 to 2023Enrolled5ConditionsMultiple SclerosisArmsIn-phase Bilateral Exercises of the upper limbs
NCT06494657 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Frozen Shoulder: A Pragmatic Replicated N-of-1 Case Series Investigating Glucose Levels and Patient Reported Outcomes Following a Corticosteroid Injection.

TypeobservationalSponsorCentral London Community Healthcare NHS TrustRan2024 to 2025Enrolled10ConditionsFrozen Shoulder, Adhesive CapsulitisArmsCorticosteroid injection
3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michele A LoboBiomechanics & Movement Science Program, Department of Physical Therapy, University of Delaware, Newark, Delaware (M.A.L., A.B.C., I.B.); and Division of Educational Psychology & Methodology, State University of New York at Albany, Albany, New York (M.M.).
Mariola Moeyaert
Andrea Baraldi Cunha
Iryna Babik

Funding

An Innovative Device for Intervention in Infants With Nervous System InjuryR21HD076092 · NICHD · UNIVERSITY OF DELAWARE · PI LOBO, MICHELE A · 2014 to 2015
$438k
NICHD NIH HHS R21 HD076092
6 · The paper itself

Abstract

background and purposeThe purpose of this article is to describe single-case studies and contrast them with case studies and randomized clinical trials. We highlight current research designs, analysis techniques, and quality appraisal tools relevant for single-case rehabilitation research. SUMMARY OF KEY POINTS: Single-case studies can provide a viable alternative to large group studies such as randomized clinical trials. Single-case studies involve repeated measures and manipulation of an independent variable. They can be designed to have strong internal validity for assessing causal relationships between interventions and outcomes, as well as external validity for generalizability of results, particularly when the study designs incorporate replication, randomization, and multiple participants. Single-case studies should not be confused with case studies/series (ie, case reports), which are reports of clinical management of a patient or a small series of patients. RECOMMENDATIONS FOR CLINICAL PRACTICE: When rigorously designed, single-case studies can be particularly useful experimental designs in a variety of situations, such as when research resources are limited, studied conditions have low incidences, or when examining effects of novel or expensive interventions. Readers will be directed to examples from the published literature in which these techniques have been discussed, evaluated for quality, and implemented.

Indexed as

Medical RecordsQuality Assurance, Health CareResearch DesignCohort StudiesHumansRandomized Controlled Trials as Topic

Identifiers

PMID28628553
PMCPMC5492992

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.