ArticleCornea2017
Morphology and Function of Meibomian Glands and Other Tear Film Parameters in Junior High School Students.
Article in Cornea, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- The role of childhood overweight in meibomian gland dysfunction and dry eye disease in Chinese children.BMC ophthalmology · 2025Article
- Meibomian gland alterations in allergic conjunctivitis: insights from a novel quantitative analysis algorithm.Frontiers in cell and developmental biology · 2024Article
- Meibomian Gland Dysfunction Clinical Practice Guidelines.Japanese journal of ophthalmology · 2023Article
- Proposed Algorithm for Management of Meibomian Gland Dysfunction Based on Noninvasive Meibography.Journal of clinical medicine · 2020Article
- Comparison of two measurements for the lower lid margin thickness: vernier micrometer and anterior segment optical coherence tomography.International ophthalmology · 2020Article
- Electronic Device Screen Time and Meibomian Gland Morphology in Children.Journal of ophthalmic & vision researchArticle
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Authors and funding
4 authors.
Funding
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Abstract
purposeWe measured tear film parameters, including the morphology and function of meibomian glands, in junior high school students at 15 years of age.
methodsA total of 111 eyes of 111 students (56 males and 55 females) were enrolled in the study. The ocular symptom score (0-14), after-school study time, lipid layer thickness (LLT) of the tear film, partial blink rate, lid margin abnormalities (0-4), tear film breakup time, corneal and conjunctival epithelial damage (fluorescein staining score, 0-9), meiboscore as determined by noncontact meibography (0-6), Schirmer test value, and meibum grade (0-3) were determined. The relationships between parameters were evaluated with the Spearman correlation coefficient (ρ).
resultsThe meiboscore was 2.8 ± 1.2, and the meibum grade was 1.8 ± 1.2. The meiboscore significantly correlated with the meibum grade (ρ = 0.272, P = 0.004), Schirmer test value (ρ = -0.220, P = 0.021), and LLT (ρ = -0.264, P = 0.005). The breakup time significantly correlated with LLT (ρ = 0.261, P = 0.006), meibum grade (ρ = -0.338, P < 0.001), and fluorescein staining score (ρ = -0.214, P = 0.025). The partial blink rate significantly correlated with the Schirmer test value (ρ = -0.240, P = 0.011). The meiboscore (P < 0.001) and meibum grade (P = 0.032) were significantly greater in males than in females.
conclusionsThe morphology and function of meibomian glands are altered even at 15 years of age, with the changes being more prominent in males than in females.
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