Evidence map›Paper›PMID 28628382›Full record

ReviewSmall GTPases2019

UnPAKing RUNX3 functions-Both sides of the coin.

Arun Kumar, Sandhya Sundaram, Suresh K Rayala, Ganesh Venkatraman

Open access · bronzeAbstract readReview
In one paragraph

Review in Small GTPases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Arun Kumara Department of Biotechnology , Indian Institute of Technology Madras (IITM) , Chennai , India.
Sandhya Sundaramb Departments of Pathology , Sri Ramachandra University , Porur, Chennai , India.
Suresh K Rayalaa Department of Biotechnology , Indian Institute of Technology Madras (IITM) , Chennai , India.
Ganesh Venkatramanc Departments of Human Genetics , Sri Ramachandra University , Porur, Chennai , India.
Indian Institute of Technology Madras · INSri Ramachandra Institute of Higher Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post translational modifications of RUNX3 have been shown to play an important role in directing RUNX3 functions. In this review we highlight the phosphorylation dependent functions of RUNX3 as regulated by PAK1 and its implications on tumorigenesis.

Indexed as

AnimalsCore Binding Factor Alpha 3 SubunitGene Expression Regulation, NeoplasticHumansNeoplasmsp21-Activated KinasesPhosphorylationProtein Processing, Post-TranslationalCore Binding Factor Alpha 3 Subunitp21-Activated KinasesPAK1 protein, humanRunx3 protein, human

Identifiers

PMID28628382
PMCPMC6548293
OpenAlexW2654942271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.