Evidence map›Paper›PMID 28627990›Full record

ReviewThe neuroradiology journal2017

Systemic metastases from central nervous system ependymoma: case report and review of the literature.

Claudia Marsecano, Federico Bruno, Giulia Michelini, Marco Perri, Giuseppe Calvisi, Ernesto Di Cesare, Alessandra Splendiani

Open access · bronzeAbstract readCase ReportsReview
In one paragraph

Review in The neuroradiology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Metastatic Supratentorial Ependymoma: A Case Presentation and Systematic Review of the Literature.Neuropathology : official journal of the Japanese Society of Neuropathology · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Claudia Marsecano1 Department of Biotechnological and Applied Clinical Science, Division of Radiology, University of L'Aquila, L'Aquila, Italy.
Federico Bruno1 Department of Biotechnological and Applied Clinical Science, Division of Radiology, University of L'Aquila, L'Aquila, Italy.
Giulia Michelini1 Department of Biotechnological and Applied Clinical Science, Division of Radiology, University of L'Aquila, L'Aquila, Italy.
Marco Perri1 Department of Biotechnological and Applied Clinical Science, Division of Radiology, University of L'Aquila, L'Aquila, Italy.
Giuseppe Calvisi2 Department of Pathology, S. Salvatore Hospital L'Aquila, L'Aquila, Italy.
Ernesto Di Cesare1 Department of Biotechnological and Applied Clinical Science, Division of Radiology, University of L'Aquila, L'Aquila, Italy.
Alessandra Splendiani1 Department of Biotechnological and Applied Clinical Science, Division of Radiology, University of L'Aquila, L'Aquila, Italy.
University of L'Aquila · ITSan Salvatore Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ependymal tumours in adults are rare, accounting for less than 4% of primary tumours of the central nervous system, and exceptionally metastasise outside the nervous system. In this study, we present a case of anaplastic ependymoma, which developed metastases outside the nervous system less than a year after its clinical onset. A healthy 65-year-old woman suddenly presented with drowsiness of unknown origin, accompanied by ingravescent fatigue, inability to maintain the upright posture, headache, nausea and vomiting. Computed tomography study performed in the emergency department showed the presence of an inhomogeneously hypodense area, with temporoparietal extension and median line deviation. After surgical excision, performed after two days, the bioptic examination demonstrated an anaplastic ependymoma with multiple areas of necrosis. The patient was submitted to adjuvant radiation therapy. At magnetic resonance imaging follow-up, performed three months after surgery, neither local recurrences nor typical 'drop metastases' to the spinal area were observed. Three months later, magnetic resonance imaging control revealed bone metastases and recurrences in the left insula and at the ipsilateral cerebellar hemisphere. Total body computed tomography examination showed metastases in the liver, vertebrae and pelvic bones, and involvement of paratracheal lymph nodes.

Indexed as

AgedBrain NeoplasmsEpendymomaFemaleHumansMagnetic Resonance ImagingNecrosisNeoplasm GradingNeoplasm MetastasisTomography, X-Ray ComputedWhole Body ImagingAnaplastic ependymomabrain tumoursependymal tumoursependymomaependymomas grade IIImetastasesrecurrence of anaplastic ependymoma

Identifiers

PMID28627990
PMCPMC5480795
OpenAlexW2591159794

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.