Evidence map›Paper›PMID 28627407›Full record

ArticleToxicology2017

Sources, mechanisms, and consequences of chemical-induced mitochondrial toxicity.

Joel N Meyer, Sherine S L Chan

Abstract readEditorial
In one paragraph

Article in Toxicology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Observational
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Mitochondrial Toxicity.Toxicological sciences : an official journal of the Society of Toxicology · 2018
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joel N MeyerNicholas School of the Environment and Integrated Toxicology and Environmental Health Program, Duke University, Durham, NC, 27708-0328, USA. Electronic address: joel.meyer@duke.edu.
Sherine S L ChanDrug Discovery and Biomedical Sciences, College of Pharmacy, Medical University of South Carolina, Charleston, SC, 29425, USA; Neuroene Therapeutics, Mt. Pleasant, SC 29464, USA. Electronic address: chans@musc.edu.

Funding

Zebrafish as a Detector of Organophosphate ExposureP42ES010356 · NIEHS · DUKE UNIVERSITY · PI AMY H HERRING · 2000 to 2026
$56.2M
The Role of Mitochondrial DNA Damage in NeurodegenerationR01ES017540 · NIEHS · DUKE UNIVERSITY · PI MEYER, JOEL NEWMAN · 2011 to 2015
$1.8M
Adverse Actions of Stimulants on Embryonic Development and EnergeticsR21DA037706 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI CHAN, SHERINE S · 2014 to 2015
$409k
Novel mechanism for the treatment of epilepsy: New Vitamin K analogs target energetics and have low toxicity due to excellent specificity and low dose requirements compared to current therapiesR41NS097047 · NINDS · NEUROENE THERAPEUTICS INC · PI CHAN, SHERINE S · 2016 to 2016
$225k
NIDA NIH HHS R21 DA037706NIEHS NIH HHS P42 ES010356NIEHS NIH HHS R01 ES017540NINDS NIH HHS R41 NS097047
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsArsenicDNA, MitochondrialHumansMitochondriaMitochondrial DiseasesReactive Oxygen SpeciesReverse Transcriptase InhibitorsArsenicDNA, MitochondrialReactive Oxygen SpeciesReverse Transcriptase Inhibitors

Identifiers

PMID28627407
PMCPMC5681391

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.