Evidence map›Paper›PMID 28627305›Full record

ArticleJournal of diabetes science and technology2017

Variability of Diabetes Alert Dog Accuracy in a Real-World Setting.

Linda A Gonder-Frederick, Jesse H Grabman, Jaclyn A Shepard, Anand V Tripathi, Dallas M Ducar, Zachary R McElgunn

Abstract read
In one paragraph

Article in Journal of diabetes science and technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Interactions between the Public and Assistance Dog Handlers and Trainers.Animals : an open access journal from MDPI · 2021
    Article
  6. Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Linda A Gonder-Frederick1 Behavioral Medicine Center, University of Virginia Health System, Charlottesville, VA, USA.
Jesse H Grabman1 Behavioral Medicine Center, University of Virginia Health System, Charlottesville, VA, USA.
Jaclyn A Shepard1 Behavioral Medicine Center, University of Virginia Health System, Charlottesville, VA, USA.
Anand V Tripathi1 Behavioral Medicine Center, University of Virginia Health System, Charlottesville, VA, USA.
Dallas M Ducar1 Behavioral Medicine Center, University of Virginia Health System, Charlottesville, VA, USA.
Zachary R McElgunn1 Behavioral Medicine Center, University of Virginia Health System, Charlottesville, VA, USA.

Funding

Accuracy of Blood Glucose Detection by Diabetes Alert Dogs (DADs)R21DK099697 · NIDDK · UNIVERSITY OF VIRGINIA · PI GONDER-FREDERICK, LINDA ANN · 2013 to 2014
$435k
NIDDK NIH HHS R21 DK099697
6 · The paper itself

Abstract

backgroundDiabetes alert dogs (DADs) are growing in popularity as an alternative method of glucose monitoring for individuals with type 1 diabetes (T1D). Only a few empirical studies have assessed DAD accuracy, with inconsistent results. The present study examined DAD accuracy and variability in performance in real-world conditions using a convenience sample of owner-report diaries.

methodEighteen DAD owners (44.4% female; 77.8% youth) with T1D completed diaries of DAD alerts during the first year after placement. Diary entries included daily BG readings and DAD alerts. For each DAD, percentage hits (alert with BG ≤ 5.0 or ≥ 11.1 mmol/L; ≤90 or ≥200 mg/dl), percentage misses (no alert with BG out of range), and percentage false alarms (alert with BG in range) were computed. Sensitivity, specificity, positive likelihood ratio (PLR), and true positive rates were also calculated.

resultsOverall comparison of DAD Hits to Misses yielded significantly more Hits for both low and high BG. Total sensitivity was 57.0%, with increased sensitivity to low BG (59.2%) compared to high BG (56.1%). Total specificity was 49.3% and PLR = 1.12. However, high variability in accuracy was observed across DADs, with low BG sensitivity ranging from 33% to 100%. Number of DADs achieving ≥ 60%, 65% and 70% true positive rates was 71%, 50% and 44%, respectively.

conclusionsDADs may be able to detect out-of-range BG, but variability across DADs is evident. Larger trials are needed to further assess DAD accuracy and to identify factors influencing the complexity of DAD accuracy in BG detection.

Indexed as

DogsAnimalsBlood GlucoseBlood Glucose Self-MonitoringDiabetes Mellitus, Type 1FemaleHumansMaleSensitivity and SpecificityBlood Glucoseblood glucose detectiondiabetes alert dogservice dogtype 1 diabetes

Identifiers

PMID28627305
PMCPMC5588823

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.