Evidence map›Paper›PMID 28627237›Full record

ArticleIntegrative cancer therapies2018

Characteristic Analysis of Complementary and Alternative Medicine in Randomized Controlled Trials of Oncology: A Comparison of Published Studies.

Huiqing Zhang, Geliang Yang, Wei Zhang, Wei Gu, Yonghua Su, Changquan Ling

Abstract read
In one paragraph

Article in Integrative cancer therapies, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Huiqing Zhang1 Changhai Hospital of Traditional Chinese Medicine, Second Military Medical University, Shanghai, China.
Geliang Yang1 Changhai Hospital of Traditional Chinese Medicine, Second Military Medical University, Shanghai, China.
Wei Zhang2 Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, China.
Wei Gu1 Changhai Hospital of Traditional Chinese Medicine, Second Military Medical University, Shanghai, China.
Yonghua Su1 Changhai Hospital of Traditional Chinese Medicine, Second Military Medical University, Shanghai, China.
Changquan Ling1 Changhai Hospital of Traditional Chinese Medicine, Second Military Medical University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComplementary and alternative medicine (CAM) has been widely used by cancer patients and oncologists in the past decades. The present study aimed to examine and compare the characteristics and registration status of published studies in a sample of recently published CAM randomized controlled trial (RCT) reports of oncology in leading journals of 3 categories: general and internal medicine (GIM), clinical oncology (CO), and CAM.

methodsArticles published in the top 5 journals of the 3 categories from 2006 to 2015 were searched in PubMed. Basic characteristics, registration information, impact factor, and citations were identified and extracted from the included RCTs. Data were summarized by frequency, mean, and median and compared using χ

resultsA total of 59 RCTs were included; among them, 34 (58%) could be identified with a registration number. GIM journals (15) enjoyed the highest average number of citations per article, followed by CO (12) and CAM (3) journals ( P < .0001). ClinicalTrials.gov was the most popular registry for these RCTs. Of the RCTs registered in ClinicalTrials.gov , 24% (4/17) of the published studies in CO journals put their results in the registry; however, no study in GIM and CAM journals put the result in the registry ( P = .372).

conclusionThe top GIM, CO, and CAM journals rarely published CAM RCTs of oncology from 2006 to 2015, and the CAM articles of oncology were less cited. However, there was a clear improvement in the trial registration rate over the past decades.

Indexed as

Clinical Trials as TopicComplementary TherapiesHumansJournal Impact FactorMedical OncologyNeoplasmsRandomized Controlled Trials as TopicRegistriescomparisoncomplementary and alternative medicineoncologyRCTregister

Identifiers

PMID28627237
PMCPMC6041924

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.