Evidence map›Paper›PMID 28627138›Full record

ArticleCancer medicine2017

Predictors of BRCA1/2 genetic testing among Black women with breast cancer: a population-based study.

Tarsha Jones, Anne Marie McCarthy, Younji Kim, Katrina Armstrong

Abstract read
In one paragraph

Article in Cancer medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Frontiers in oncology · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Intersectionality,Cancers · 2024
    Article
  10. Onco-Breastomics: An Eco-Evo-Devo Holistic Approach.International journal of molecular sciences · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tarsha JonesFlorida Atlantic University, Boca Raton, Florida.ORCID http://orcid.org/0000-0003-2118-5780
Anne Marie McCarthyMassachusetts General Hospital, Boston, Massachusetts.
Younji KimMassachusetts General Hospital, Boston, Massachusetts.
Katrina ArmstrongMassachusetts General Hospital, Boston, Massachusetts.

Funding

Racial Differences in BRCA1/2 Testing: Patients or Providers?R01CA133004 · NCI · UNIVERSITY OF PENNSYLVANIA · PI GROENEVELD, PETER W. · 2009 to 2013
$2.5M
NCI NIH HHS R01 CA133004
6 · The paper itself

Abstract

Evidence shows that Black women diagnosed with breast cancer are substantially less likely to undergo BRCA testing and other multipanel genetic testing compared to White women, despite having a higher incidence of early-age onset breast cancer and triple-negative breast cancer (TNBC). Our study identifies predictors of BRCA testing among Black women treated for breast cancer and examines differences between BRCA testers and nontesters. We conducted an analysis of 945 Black women ages 18-64 diagnosed with localized or regional-stage invasive breast cancer in Pennsylvania and Florida between 2007 and 2009. Logistic regression was used to identify predictors of BRCA 1/2 testing. Few (27%) (n = 252) of the participants reported having BRCA testing. In the multivariate analysis, we found that perceived benefits of BRCA testing (predisposing factor) ([OR], 1.16; 95% CI: 1.11-1.21; P < 0.001), income (enabling factor) ([OR], 2.10; 95% CI: 1.16-3.80; p = 0.014), and BRCA mutation risk category (need factor) ([OR], 3.78; 95% CI: 2.31-6.19; P < 0.001) predicted BRCA testing. These results suggest that interventions to reduce disparities in BRCA testing should focus on identifying patients with high risk of mutation, increasing patient understanding of the benefits of BRCA testing, and removing financial and other administrative barriers to genetic testing.

Indexed as

Genes, BRCA1Genes, BRCA2AdolescentAdultBreast NeoplasmsComorbidityFemaleFloridaGenetic Predisposition to DiseaseGenetic TestingHumansMiddle AgedMutationOdds RatioPennsylvaniaPopulation SurveillanceBlack womenBRCA 1/2 testingbreast cancercancer preventiongenetics

Identifiers

PMID28627138
PMCPMC5504315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.