ArticleMaternal & child nutrition2018
Should women be advised to use calcium supplements during pregnancy? A decision analysis.
Article in Maternal & child nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Calcium Supplementation in Pregnancy: A Systematic Review of Clinical Studies.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Preeclampsia: Insights into pathophysiological mechanisms and preventive strategies.American journal of preventive cardiology · 2025Review
- The interval between the onset of increased blood pressure and proteinuria in preeclampsia and the contributing factors.Archives of gynecology and obstetrics · 2024Article
- Article
- Counseling pregnant women on calcium: effects on calcium intake.Journal of perinatal medicine · 2023Article
- The risk matrix approach: a helpful tool weighing probability and impact when deciding on preventive and diagnostic interventions.BMC health services research · 2022Article
- Dietary factors that affect the risk of pre-eclampsia.BMJ nutrition, prevention & health · 2022Review
- iDISK: the integrated DIetary Supplements Knowledge base.Journal of the American Medical Informatics Association : JAMIA · 2020Article
- Calcium intake from diet and supplement use during early pregnancy: the Expect study I.European journal of nutrition · 2020Article
- Implementing a Preeclampsia Prediction Model in Obstetrics: Cutoff Determination and Health Care Professionals' Adherence.Medical decision making : an international journal of the Society for Medical Decision Making · 2020Article
- Calcium intake in high-risk pregnant women assisted in a high-complexity hospital.Molecular biology reports · 2019Article
- The International Federation of Gynecology and Obstetrics (FIGO) initiative on pre-eclampsia: A pragmatic guide for first-trimester screening and prevention.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2019Article
- Implementation and Effects of Risk-Dependent Obstetric Care in the Netherlands (Expect Study II): Protocol for an Impact Study.JMIR research protocols · 2018Article
- Should women be advised to use calcium supplements during pregnancy? A decision analysis.Maternal & child nutrition · 2018Article
- Nutritional Status and Nutrients Related to Pre-Eclampsia Risk.American journal of lifestyle medicineArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adequate calcium intake during pregnancy is important in the prevention of pre-eclampsia. A substantial proportion of pregnant women do not meet the recommended daily calcium intake, even in developed countries. Nonetheless, calcium supplementation is not routinely advised to pregnant women in most countries. We aimed to predict the impact of advising pregnant women to use calcium supplements (1,000 mg/day) on the number of cases of pre-eclampsia prevented and related health care costs. By use of a decision-analytic model, we assessed the expected impact of advising calcium supplementation to either (1) all pregnant women, (2) women at high risk of developing pre-eclampsia, or (3) women with a low dietary calcium intake compared with current care. Calculations were performed for a hypothetical cohort of 100,000 pregnant women living in a high-income country, although input parameters of the model can be adjusted so as to fit other settings. The incidence of pre-eclampsia could be reduced by 25%, 8%, or 13% when advising calcium supplementation to all pregnant women, women at high risk of pre-eclampsia, or women with a low dietary calcium intake, respectively. Expected net financial benefits of the three scenarios were of €4,621,465, €2,059,165, or €2,822,115 per 100,000 pregnant women, respectively. Advising pregnant women to use calcium supplements can be expected to cause substantial reductions in the incidence of pre-eclampsia as well as related health care costs. It appears most efficient to advise calcium supplementation to all pregnant women, not subgroups only.
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