ReviewJournal of current ophthalmology2017
Part-time versus full-time occlusion therapy for treatment of amblyopia: A meta-analysis.
Review in Journal of current ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04238065 (A Phase 3 Randomized, Single-blind, Multicenter, Clinical Control Study to Evaluate the Efficacy and Safety of Caterna Virtual Reality Facilitating Treatment Patients With Amblyopia in Children), which is not on this map. Cited by 12 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Phase 3 Randomized, Single-blind, Multicenter, Clinical Control Study to Evaluate the Efficacy and Safety of Caterna Virtual Reality Facilitating Treatment Patients With Amblyopia in Children
Who cites it
12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Amblyopia Preferred Practice Pattern.Ophthalmology · 2023Guideline
- Pooled it
- Efficacy of vision-based treatments for children and teens with amblyopia: a systematic review and meta-analysis of randomised controlled trials.BMJ open ophthalmology · 2021Pooled it
- Efficacy of interventions for amblyopia: a systematic review and network meta-analysis.BMC ophthalmology · 2020Pooled it
- Syntonic phototherapy versus part time occlusion for treatment of refractive amblyopia.Scientific reports · 2025Trial
- Portable rotating grating stimulation for anisometropic amblyopia with 6 months training.Scientific reports · 2021Trial
- Amblyopia in 2026: A State-of-the-Art Review of Multidimensional Phenotyping, Response Heterogeneity, and Clinical Considerations.Brain sciences · 2026Review
- Factors affecting the total occlusion time in eyes with hyperopic anisometropic amblyopia.BMC ophthalmology · 2023Article
- Management of amblyopia in pediatric patients: Current insights.Eye (London, England) · 2022Review
- Commentary: Part time occlusion for amblyopia: The unsung hero!Indian journal of ophthalmology · 2021Article
- Comparison between Amblyopia Treatment with Glasses Only and Combination of Glasses and Open-Type Binocular "Occlu-Pad" Device.BioMed research international · 2018Article
- Full time occlusion VS part time occlusion in treatment of monocular amblyopia.Pakistan journal of medical sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare full-time occlusion (FTO) and part-time occlusion (PTO) therapy in the treatment of amblyopia, with the secondary aim of evaluating the minimum number of hours of part-time patching required for maximal effect from occlusion.
methodsA literature search was performed in PubMed, Scopus, Science Direct, Ovid, Web of Science and Cochrane library. Methodological quality of the literature was evaluated according to the Oxford Center for Evidence Based Medicine and modified Newcastle-Ottawa scale. Statistical analyses were performed using
resultsThe present meta-analysis included six studies [three randomized controlled trials (RCTs) and three non-RCTs]. Pooled standardized difference in the mean changes in the visual acuity was 0.337 [lower and upper limits: -0.009, 0.683] higher in the FTO as compared to the PTO group; however, this difference was not statistically significant (
conclusionsThis meta-analysis shows no statistically significant difference between PTO and FTO in treatment of amblyopia. However, our results suggest that the minimum effective PTO duration, to observe maximal improvement in visual acuity is six hours per day.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.