Evidence map›Paper›PMID 28626786›Full record

ArticleNeurobiology of stress2017

Interaction between estradiol and 5-HT

Telma Gonçalves Carneiro Spera de Andrade, João Victor Dos Santos Silva, Matheus Fitipaldi Batistela, Fernando Frei, Ana Beatriz Sant'Ana

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurobiology of stress, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Telma Gonçalves Carneiro Spera de AndradeUNESP - Univ Estadual Paulista, FCL, Department of Biological Science, Avenida Dom Antonio, 2100, 19.806-900 Assis, São Paulo, Brazil.
João Victor Dos Santos SilvaLaboratory of Physiology, UNESP, Assis, São Paulo, Brazil.
Matheus Fitipaldi BatistelaLaboratory of Physiology, UNESP, Assis, São Paulo, Brazil.
Fernando FreiUNESP - Univ Estadual Paulista, FCL, Department of Biological Science, Avenida Dom Antonio, 2100, 19.806-900 Assis, São Paulo, Brazil.
Ana Beatriz Sant'AnaLaboratory of Physiology, UNESP, Assis, São Paulo, Brazil.
Universidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The median raphe nucleus (MRN) is related to stress resistance and defensive responses, a crucial source of serotonergic neurons that project to prosencephalic structures related to stress and anxiety. Estrogen receptors were identified in this mesencephalic structure. It is possible that the estrogen action is related to serotonin effect on somatodendritic 5-HT

Indexed as

5-HT1A receptorsAnxietyContextual conditioningEstradiol benzoateMedian raphe nucleusOvariectomized ratsWAY100.635

Identifiers

PMID28626786
PMCPMC5470534
OpenAlexW2618980240

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.