Trial reportBioMed research international2017
ACTN3 Gene and Susceptibility to Sarcopenia and Osteoporotic Status in Older Korean Adults.
Trial report in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Sex-specific physical activity thresholds influencing muscle function in older adults with XX genotype of ACTN3 R577X.Scientific reports · 2026Article
- The Potential of MicroRNAs in the Context of Sarcopenic Obesity.Physiological research · 2025Review
- Review
- Review
- Association of alpha-actinin-3 genotype with muscle mass and physical function in community-dwelling older adults.European geriatric medicine · 2025Article
- Sarcopenic obesity in older adults: a clinical overview.Nature reviews. Endocrinology · 2024Review
- Research Progress on the Effect and Mechanism of Exercise Intervention on Sarcopenia Obesity.Clinical interventions in aging · 2024Review
- Associations of the Alpha-Actinin Three Genotype with Bone and Muscle Mass Loss among Middle-Aged and Older Adults.Journal of clinical medicine · 2022Article
- Polygenic Models Partially Predict Muscle Size and Strength but Not Low Muscle Mass in Older Women.Genes · 2022Article
- Is there a relationship between ACTN3 R577X gene polymorphism and sarcopenia?Aging clinical and experimental research · 2022Article
- Effect of the ACTN-3 gene polymorphism on functional fitness and executive function of elderly.Frontiers in aging neuroscience · 2022Article
- Sarcopenia, Obesity, and Sarcopenic Obesity: Relationship with Skeletal Muscle Phenotypes and Single Nucleotide Polymorphisms.Journal of clinical medicine · 2021Article
- ACTN3 Genotypes and Their Relationship with Muscle Mass and Function of Kosovan Adults.International journal of environmental research and public health · 2021Article
- Article
- The Effect ofFrontiers in genetics · 2021Article
- The Association of Multiple Gene Variants with Ageing Skeletal Muscle Phenotypes in Elderly Women.Genes · 2020Article
- Prevalence and association of single nucleotide polymorphisms with sarcopenia in older women depends on definition.Scientific reports · 2020Article
- Distribution of allele frequencies for genes associated with physical activity and/or physical capacity in a homogenous Norwegian cohort- a cross-sectional study.BMC genetics · 2020Article
- Pilot Study on Genetic Associations With Age-Related Sarcopenia.Frontiers in genetics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLittle information is available about molecular markers for sarcopenia and osteoporosis in Asian populations.
objectiveThis study investigated the association of the
methodsOlder Korean 62 men and 270 women (mean age 73.7 ± 6.6 years) participated in this study. Body mass index, percent body fatness, appendicular skeletal muscle mass, and bone mineral density of the lumbar spine, femur, and total body were analyzed with dual-energy X-ray absorptiometry.
resultsDetermination of odds ratios (ORs) and 95% confidence intervals (CIs) using binary logistic regression analyses showed that XX homozygotes were at a significantly higher risk of sarcopenia (OR = 2.056, 95% CI = 1.024-4.127,
conclusionOur findings suggest that the
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.