Evidence map›Paper›PMID 28626712›Full record

ArticleBiotechnology reports (Amsterdam, Netherlands)2015

Modification of a bi-functional diguanylate cyclase-phosphodiesterase to efficiently produce cyclic diguanylate monophosphate.

Natasha M Nesbitt, Dhruv P Arora, Roger A Johnson, Elizabeth M Boon

Open access · goldAbstract read
In one paragraph

Article in Biotechnology reports (Amsterdam, Netherlands), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Differential ligand-selective control of opposing enzymatic activities within a bifunctional c-di-GMP enzyme.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  4. Article
  5. Article
  6. Review
  7. Redefining genomic view ofDrug target insights
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Natasha M NesbittDepartment of Chemistry, Stony Brook University, Stony Brook, NY 11794-3400 United States.
Dhruv P AroraDepartment of Chemistry, Stony Brook University, Stony Brook, NY 11794-3400 United States.
Roger A JohnsonDepartment of Chemistry, Stony Brook University, Stony Brook, NY 11794-3400 United States.
Elizabeth M BoonDepartment of Chemistry, Stony Brook University, Stony Brook, NY 11794-3400 United States.
Stony Brook University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclic-diGMP is a bacterial messenger that regulates many physiological processes, including many attributed to pathogenicity. Bacteria synthesize cyclic-diGMP from GTP using diguanylate cyclases; its hydrolysis is catalyzed by phosphodiesterases. Here we report the over-expression and purification of a bi-functional diguanylate cyclase-phosphodiesterase from

Indexed as

[32P]-cyclic-diGMPAvHaCE, Agrobacterium vitis H-NOX associated cyclic-diGMP processing enzymeCyclic-diGMPCyclic-diGMP, bis-3′-5′-cyclic dimeric guanosine monophosphateDGC, diguanylate cyclaseDiguanylate cyclaseGTP, guanosine-5′-triphosphateH-NOX associated cyclic-diGMP processing enzymePDE, phosphodiesterasepGpG, 5′-phosphoguanylyl-(3′,5′)-guanosine)Phosphodiesterase

Identifiers

PMID28626712
PMCPMC5466042
OpenAlexW244760573

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.