Evidence map›Paper›PMID 28626453›Full record

ArticleFrontiers in microbiology2017

Zinc Oxide Nanoparticles Influence Microflora in Ileal Digesta and Correlate Well with Blood Metabolites.

Yanni Feng, Lingjiang Min, Weidong Zhang, Jing Liu, Zhumei Hou, Meiqiang Chu, Lan Li, Wei Shen, Yong Zhao, Hongfu Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Impact of dietary zinc nanoparticles and probiotics on broiler health and productivity.Journal of advanced veterinary and animal research · 2025
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  10. Influence of heavy metal exposure on gut microbiota: Recent advances.Journal of biochemical and molecular toxicology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yanni FengCollege of Animal Science and Technology, Qingdao Agricultural UniversityQingdao, China.
Lingjiang MinCollege of Animal Science and Technology, Qingdao Agricultural UniversityQingdao, China.
Weidong ZhangCollege of Animal Science and Technology, Qingdao Agricultural UniversityQingdao, China.
Jing LiuCore Laboratories of Qingdao Agricultural UniversityQingdao, China.
Zhumei HouCollege of Marine Science and Technology, Qingdao Agricultural UniversityQingdao, China.
Meiqiang ChuCollege of Animal Science and Technology, Qingdao Agricultural UniversityQingdao, China.
Lan LiCollege of Animal Science and Technology, Qingdao Agricultural UniversityQingdao, China.
Wei ShenCollege of Animal Science and Technology, Qingdao Agricultural UniversityQingdao, China.
Yong ZhaoCollege of Animal Science and Technology, Qingdao Agricultural UniversityQingdao, China.
Hongfu ZhangState Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural SciencesBeijing, China.
Qingdao Agricultural University · CNChinese Academy of Agricultural Sciences · CNInstitute of Animal Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zinc oxide nanoparticles (ZnO NPs) are used widely in consumer and industrial products, however, their influence on gut microbiota and metabolism and their mutual interactions are not fully understood. In this study, the effects of ZnO NPs on ileal bacterial communities, plasma metabolites, and correlations between them were investigated. Hens were fed with different concentrations of ZnO NPs [based on Zn; 0 mg/kg (control), 25 mg/kg, 50 mg/kg, and 100 mg/kg] for 9 weeks. Subsequently, ileal digesta and blood plasma were collected for analysis of microflora and metabolites, respectively. The V3-V4 region of the 16S rRNA gene of ileal digesta microbiota was sequenced using the Illumina HiSeq 2500 platform. The predominant bacterial community in the ileum belongs to the phylum Firmicutes. The richness of the bacterial community was negatively correlated with increasing amounts of ZnO NPs (

Indexed as

correlationileal digestametabolismmicrofloraZnO nanoparticles

Identifiers

PMID28626453
PMCPMC5454036
OpenAlexW2620564695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.