Evidence map›Paper›PMID 28626043›Full record

ReviewPharmacological reviews2017

The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling.

Yuri K Peterson, Louis M Luttrell

Open access · bronzeAbstract readReview
In one paragraph

Review in Pharmacological reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 252 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
252citing papers in PubMed, 1 pooled it
19.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

252 citing papers in PubMed, 1 synthesis or guideline pooled it, 420 citations in OpenAlex.

  1. The Signaling and Pharmacology of the Dopamine D1 Receptor.Frontiers in cellular neuroscience · 2021
    Pooled it
  2. Review
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  17. Beta arrestin 1 is a key regulator of pulmonary vascular tone.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  18. Article
  19. Review
  20. Review

192 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yuri K PetersonDepartment of Drug Discovery and Biomedical Sciences, College of Pharmacy (Y.K.P.), and Departments of Medicine and Biochemistry and Molecular Biology (L.M.L.), Medical University of South Carolina, Charleston, South Carolina; and Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina (L.M.L.).
Louis M LuttrellDepartment of Drug Discovery and Biomedical Sciences, College of Pharmacy (Y.K.P.), and Departments of Medicine and Biochemistry and Molecular Biology (L.M.L.), Medical University of South Carolina, Charleston, South Carolina; and Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina (L.M.L.) luttrell@musc.edu.
Medical University of South Carolina · US

Funding

TYROSINE KINASES IN G PROTEIN MEDIATED SIGNALINGR01DK055524 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LUTTRELL, LOUIS M · 1998 to 2017
$4.6M
Pharmacodynamics of Biased G protein-Coupled Receptor AgonismR01GM095497 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LUTTRELL, LOUIS M · 2013 to 2016
$1.1M
Functionally-selective parathyroid hormone analogs as therapeutics in metabolic bone diseaseI01BX003188 · VA · RALPH H JOHNSON VA MEDICAL CENTER · PI LUTTRELL, LOUIS M · 2017 to 2020
–
BLRD VA I01 BX003188NIDDK NIH HHS R01 DK055524NIGMS NIH HHS R01 GM095497
6 · The paper itself

Abstract

The visual/

Indexed as

AnimalsArrestinbeta-ArrestinsHumansModels, MolecularReceptors, G-Protein-CoupledSignal TransductionArrestinbeta-ArrestinsReceptors, G-Protein-Coupled

Identifiers

PMID28626043
PMCPMC5482185
OpenAlexW2626714978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.