Evidence map›Paper›PMID 28625542›Full record

ArticleInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases2017

Analysis of the codon usage of the ORF2 gene of feline calicivirus.

Minghui Zang, Wanting He, Fanshu Du, Gongjian Wu, Bohao Wu, Zhenlei Zhou

Open access · greenAbstract read
In one paragraph

Article in Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Codon Usage Bias of the Polyphenol Oxidase Genes inPlants (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Host Adaptation and Evolutionary Analysis ofFrontiers in microbiology · 2020
    Article
  11. The adaptation of codon usage of +ssRNA viruses to their hosts.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Minghui ZangCollege of Veterinary Medicine, Nanjing Agricultural University, No.1 Wei-Gang, Xuanwu District, Nanjing 210095, China.
Wanting HeCollege of Veterinary Medicine, Nanjing Agricultural University, No.1 Wei-Gang, Xuanwu District, Nanjing 210095, China.
Fanshu DuCollege of Veterinary Medicine, Nanjing Agricultural University, No.1 Wei-Gang, Xuanwu District, Nanjing 210095, China.
Gongjian WuCollege of Veterinary Medicine, Nanjing Agricultural University, No.1 Wei-Gang, Xuanwu District, Nanjing 210095, China.
Bohao WuCollege of Veterinary Medicine, Nanjing Agricultural University, No.1 Wei-Gang, Xuanwu District, Nanjing 210095, China.
Zhenlei ZhouCollege of Veterinary Medicine, Nanjing Agricultural University, No.1 Wei-Gang, Xuanwu District, Nanjing 210095, China. Electronic address: zhouzl@njau.edu.cn.
Nanjing Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feline calicivirus (FCV) is a highly prevalent pathogen of the domestic cat that causes acute infections of the oral and upper respiratory tract. The E region of the ORF2 protein is responsible for the induction of virus-neutralizing antibodies, thus it is important to understand the codon usage of this gene. Here, analysed 90 coding sequences of ORF2 and show that it undergoes a low codon usage bias. In addition, although mutational bias is one of the factors shaping the codon usage bias of this gene, natural selection plays a more significant role. Our results reveal part of the mechanisms driving FCV evolution, which will lay foundation for the further research of FCV.

Indexed as

AnimalsCaliciviridae InfectionsCalicivirus, FelineCat DiseasesCatsCodonGenes, ViralCodonCodon usageFeline calicivirusMutation pressureNatural selectionNeutrality analysisOpen reading frame 2 (ORF2)

Identifiers

PMID28625542
PMCPMC7106028
OpenAlexW2625255676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.