Evidence map›Paper›PMID 28625517›Full record

ArticleEBioMedicine2017

Reduced TDP-43 Expression Improves Neuronal Activities in a Drosophila Model of Perry Syndrome.

Yuka Hosaka, Tsuyoshi Inoshita, Kahori Shiba-Fukushima, Changxu Cui, Taku Arano, Yuzuru Imai, Nobutaka Hattori

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EBioMedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. DCTN1 Binds to TDP-43 and Regulates TDP-43 Aggregation.International journal of molecular sciences · 2021
    Article
  7. Analysis of Dopaminergic Functions in Drosophila.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yuka HosakaDepartment of Neurology, Juntendo University, Graduate School of Medicine, Tokyo 113-8421, Japan.
Tsuyoshi InoshitaDepartment of Treatment and Research in Multiple Sclerosis and Neuro-intractable Disease, Juntendo University, Graduate School of Medicine, Tokyo 113-8421, Japan.
Kahori Shiba-FukushimaDepartment of Treatment and Research in Multiple Sclerosis and Neuro-intractable Disease, Juntendo University, Graduate School of Medicine, Tokyo 113-8421, Japan.
Changxu CuiDepartment of Research for Parkinson's Disease, Juntendo University, Graduate School of Medicine, Tokyo 113-8421, Japan.
Taku AranoCenter for Genomic and Regenerative Medicine, Juntendo University, Graduate School of Medicine, Tokyo 113-8421, Japan.
Yuzuru ImaiDepartment of Neurology, Juntendo University, Graduate School of Medicine, Tokyo 113-8421, Japan; Department of Treatment and Research in Multiple Sclerosis and Neuro-intractable Disease, Juntendo University, Graduate School of Medicine, Tokyo 113-8421, Japan. Electronic address: yzimai@juntendo.ac.jp.
Nobutaka HattoriDepartment of Neurology, Juntendo University, Graduate School of Medicine, Tokyo 113-8421, Japan; Department of Treatment and Research in Multiple Sclerosis and Neuro-intractable Disease, Juntendo University, Graduate School of Medicine, Tokyo 113-8421, Japan; Department of Research for Parkinson's Disease, Juntendo University, Graduate School of Medicine, Tokyo 113-8421, Japan. Electronic address: nhattori@juntendo.ac.jp.
Juntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinsonian Perry syndrome, involving mutations in the dynein motor component dynactin or p150

Indexed as

Gene Expression RegulationAction PotentialsAnimalsAxonal TransportDepressionDisease Models, AnimalDNA-Binding ProteinsDopamineDrosophilaDrosophila ProteinsHypoventilationImmunohistochemistryMaleMotor ActivityMotor NeuronsMutationDNA-Binding ProteinsDopamineDrosophila ProteinsTBPH protein, DrosophilaAxonal transportDopamineDynactinNeurodegenerationParkinsonian syndromeTDP-43

Identifiers

PMID28625517
PMCPMC5514405
OpenAlexW2622313229

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.