ArticleCardiology in the young2017
Preoperative malnutrition is associated with increased mortality and adverse outcomes after paediatric cardiac surgery.
Article in Cardiology in the young, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 4 syntheses or guidelines pooled it, 96 citations in OpenAlex.
- Breastfeeding infants with CHD: an evidence summary and recommendations from the Cardiac Newborn Neuroprotective Network, a special interest group of the Cardiac Neurodevelopmental Outcome Collaborative.Cardiology in the young · 2025Guideline
- Preoperative nutrition status in children with congenital heart disease and its impact on postoperative outcomes: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Triiodothyronine Supplementation for Children Undergoing Cardiopulmonary Bypass: A Meta-Analysis.Pediatric cardiology · 2024Pooled it
- The development of a consensus-based nutritional pathway for infants with CHD before surgery using a modified Delphi process.Cardiology in the young · 2018Guideline
- Improving preoperative enteral feeding for newborns with congenital heart disease.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Reducing surgical site infections in paediatric cardiac surgery in a resource-constrained setting: a quality improvement initiative.BMJ open quality · 2026Article
- Preoperative decision tree model for predicting pulmonary valve-sparing repair in humanitarian pediatric tetralogy of fallot patients.Journal of cardiothoracic surgery · 2026Article
- Improving Pulmonary Edema Assessment in Pediatric Congenital Heart Disease: The Role of Lung Ultrasonography.Arquivos brasileiros de cardiologia · 2026Article
- Preoperative prognostic nutritional index and in-hospital mortality in neonates undergoing cardiac surgery for congenital heart disease: a single-center retrospective study.Frontiers in nutrition · 2026Article
- Improving nutrition in pediatric heart failure.JHLT open · 2025Review
- The Association Between Preoperative Malnutrition and Early Postoperative Outcomes in Children with Congenital Heart Disease: A 2-Year Retrospective Study at a Lebanese Tertiary Medical Center.Children (Basel, Switzerland) · 2025Article
- Predictors of successful pulmonary valve-sparing repair in pediatric humanitarian patients with Tetralogy of Fallot.Journal of cardiothoracic surgery · 2025Article
- Growth Characteristics at Time of Fontan Procedure and Their Association with Long-Term Outcomes.The Journal of pediatrics · 2025Article
- Enhanced recovery after paediatric cardiac surgery.BJA education · 2025Review
- Feeding Approach to Optimizing Nutrition in Infants with Congenital Heart Disease.Journal of cardiovascular development and disease · 2025Review
- The incidence and risk factors of gastrointestinal dysfunction during enteral nutrition in mechanically ventilated critically ill patients.Nursing open · 2024Observational
- Feeding intolerance after pediatric cardiac surgery is associated with dysbiosis, barrier dysfunction, and reduced short-chain fatty acids.American journal of physiology. Gastrointestinal and liver physiology · 2024Article
- Preoperative Malnutrition Increases Risk of In-Hospital Mortality, Major Infection, and Longer Intensive Care Unit Stay After Ventricular Septal Defect Closure.Journal of the American Heart Association · 2024Article
- Early weight measures and long-term neuropsychological outcome of critically ill neonates and infants: a secondary analysis of the PEPaNIC trial.European journal of pediatrics · 2024Article
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Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundMalnutrition is common in children with CHD and is likely to place them at an increased risk for adverse surgical outcomes. We sought to evaluate the impact of preoperative malnutrition on outcomes after paediatric cardiac surgery.
methodsWe conducted a retrospective analysis of patients from age 0 to 5 years undergoing cardiac surgery at Seattle Children's Hospital from 2006 to 2015. We used regression modelling to examine the impact of malnutrition on surgical outcomes.
resultsWe found a non-linear relationship between low height-for-age and weight-for-age z-scores and mortality after surgery. In the range of z-score ⩽-2, each additional unit decrease in height-for-age or weight-for-age z-score was associated with a 2.9 or 2.1% increased risk for mortality, respectively. Each unit decrease in height-for-age z-score was associated with a 1.2% increased risk for cardiac arrest, 1.1% increased risk for infection, and an average of 1.7 additional hours of mechanical ventilation, 6 hours longer ICU stay, and 13 hours longer hospital stay. Each unit decrease in weight-for-age z-score was associated with a 0.7% increased risk for cardiac arrest, 0.8% increased risk for infection, and an average of 1.9 additional hours of mechanical ventilation and 5.3 additional hours of ICU stay.
conclusionsThis study is unique in demonstrating a significant association between malnutrition and 30-day mortality and other adverse outcomes after paediatric cardiac surgery in a mixed population of CHD patients. By evaluating nutritional status as a continuous variable, we were able to clearly distinguish the point at which malnutrition begins to affect mortality.
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