ReviewCritical care (London, England)2017
Transpulmonary thermodilution: advantages and limits.
Review in Critical care (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 124 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Complications Related to Transpulmonary Thermodilution in the Intensive Care Unit and the Operating Room
Hemodynamic Characteristics of Patients With SARS-CoV-2: PiCCOVID Study
Comparison of Extra Vascular Lung Water Index in Covid-19 ARDS and "Typical"ARDS Patients
Who cites it
124 citing papers in PubMed, 4 syntheses or guidelines pooled it, 296 citations in OpenAlex.
- Agreement of minimally invasive pulse wave analysis with pulmonary artery and transpulmonary thermodilution cardiac output measurements in perioperative and intensive care medicine: a systematic review and meta-analysis.British journal of anaesthesia · 2026Pooled it
- Hemodynamic monitoring strategies in cardiac surgery: an update systematic review.Journal of clinical monitoring and computing · 2026Pooled it
- Superior vena cava collapsibility index as a predictor of fluid responsiveness: a systematic review with meta-analysis.Anaesthesiology intensive therapy · 2024Pooled it
- Extravascular lung water levels are associated with mortality: a systematic review and meta-analysis.Critical care (London, England) · 2022Pooled it
- Bioimpedance based determination of cardiac index does not show enough trueness for point of care use in patients with systolic heart failure.Journal of clinical monitoring and computing · 2023Trial
- Efficacy and safety of intravenous imatinib in COVID-19 ARDS: a randomized, double-blind, placebo-controlled clinical trial.Critical care (London, England) · 2023Trial
- The increase in cardiac output induced by a decrease in positive end-expiratory pressure reliably detects volume responsiveness: the PEEP-test study.Critical care (London, England) · 2023Trial
- Effects of changes in veno-venous extracorporeal membrane oxygenation blood flow on the measurement of intrathoracic blood volume and extravascular lung water index: a prospective interventional study.Journal of clinical monitoring and computing · 2023Trial
- Ultrasound dynamic monitoring of IVCD to guide application of CRRT in patients with renal failure combined with acute heart failure.Scientific reports · 2022Trial
- Trial
- Automated echocardiography for measuring and tracking cardiac output after cardiac surgery: a validation study.Journal of clinical monitoring and computing · 2020Trial
- Integrated haemodynamic monitoring of fluid responsiveness and fluid tolerance in critical care: from physiology to bedside applications.Journal of clinical monitoring and computing · 2026Review
- Assessing fluid responsiveness in mechanically ventilated patients with intra-abdominal hypertension: a two-center, prospective, observational study.Critical care (London, England) · 2026Observational
- Pulse Index Continuous Cardiac Output-Guided Hemodynamic Therapy in Living Donor Kidney Transplantation: A Prospective Cohort Study.Journal of clinical medicine research · 2026Article
- A Novel Method for Cardiac Output and Vascular Parameters Estimation Using Peripheral Arterial Waveforms: Integrating Windkessel Model viaAnnals of biomedical engineering · 2026Article
- Are Correlation Analyses Sufficient for Cardiac Output Method Comparison?Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026Article
- Comparative assessment of extravascular lung water index in ARDS patients on veno-venous ECMO: transpulmonary thermodilution versus AI-driven chest CT segmentation.BMC pulmonary medicine · 2026Observational
- Usability of a Patch-Type Ultrasound System for Non-Invasive Hemodynamic Monitoring: A Simulation Study in Anesthesiologists.Healthcare (Basel, Switzerland) · 2026Article
- [Cardiac resuscitation-associated lung edema (CRALE): evaluation of diagnostic and therapeutic approaches by an expert group of the German Cardiac Society].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026Article
- Hemodynamic monitoring: basic principles in operation room and intensive care unit.Journal of clinical monitoring and computing · 2026Review
64 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFor complex patients in the intensive care unit or in the operating room, many questions regarding their haemodynamic management cannot be answered with simple clinical examination. In particular, arterial pressure allows only a rough estimation of cardiac output. Transpulmonary thermodilution is a technique that provides a full haemodynamic assessment through cardiac output and other indices. MAIN BODY: Through the analysis of the thermodilution curve recorded at the tip of an arterial catheter after the injection of a cold bolus in the venous circulation, transpulmonary thermodilution intermittently measures cardiac output. This measure allows the calibration of pulse contour analysis. This provides continuous and real time monitoring of cardiac output, which is not possible with the pulmonary artery catheter. Transpulmonary thermodilution provides several variables beyond cardiac output. It estimates the end-diastolic volume of the four cardiac cavities, which is a marker of cardiac preload. It provides an estimation of the systolic function of the combined ventricles. It is more direct than the pulmonary artery catheter, but does not allow the distinct estimation of right and left cardiac function. It is easier and faster to perform than echocardiography, but does not provide a full evaluation of the cardiac structure and function. Transpulmonary thermodilution has the unique advantage of being able to estimate at the bedside extravascular lung water, which quantifies the volume of pulmonary oedema, and pulmonary vascular permeability, which quantifies the degree of a pulmonary capillary leak. Both indices are helpful for guiding fluid strategy, especially in case of acute respiratory distress syndrome.
conclusionsTranspulmonary thermodilution provides a full cardiovascular evaluation that allows one to answer many questions regarding haemodynamic management. It belongs to the category of "advanced" devices that are indicated for the most critically ill and/or complex patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.