Evidence map›Paper›PMID 28624924›Full record

ReviewAbdominal radiology (New York)2017

Evaluation of hepatic fibrosis: a review from the society of abdominal radiology disease focus panel.

Jeanne M Horowitz, Sudhakar K Venkatesh, Richard L Ehman, Kartik Jhaveri, Patrick Kamath, Michael A Ohliger, Anthony E Samir, Alvin C Silva, Bachir Taouli, Michael S Torbenson and 3 more

Open access · greenAbstract readReview
In one paragraph

Review in Abdominal radiology (New York), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 1 synthesis or guideline pooled it, 132 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. The pathogenesis of liver fibrosis in Wilson's disease: hepatocyte injury and regulation mediated by copper metabolism dysregulation.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Aspirin Attenuates Liver Fibrosis via Autophagy Induction.Journal of cellular and molecular medicine · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. [Noninvasive Imaging Test to Assess Liver Fibrosis: Vibration-controlled Transient Elastography].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2024
    Review
  18. Radiology of fibrosis part II: abdominal organs.Journal of translational medicine · 2024
    Review
  19. Review
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Jeanne M HorowitzDepartment of Radiology, Feinberg School of Medicine, Northwestern University, 676 St. Clair St, Suite 800, Chicago, IL, 60611, USA. Jeanne.Horowitz@nm.org.
Sudhakar K VenkateshDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Richard L EhmanDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Kartik JhaveriDivision of Abdominal Imaging, Joint Department of Medical Imaging, University Health Network, Mt. Sinai Hospital & Women's College Hospital, University of Toronto, 610 University Ave, Toronto, ON, M5G 2M9, Canada.
Patrick KamathDivision of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Michael A OhligerDepartment of Radiology and Biomedical Imaging, UCSF School of Medicine, Zuckerberg San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA, 94110, USA.
Anthony E SamirDepartment of Radiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA.
Alvin C SilvaDepartment of Radiology, Mayo Clinic in Arizona, 13400 E. Shea Blvd., Scottsdale, AZ, 85259, USA.
Bachir TaouliDepartment of Radiology and Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, 1470 Madison Ave, Box 1234, New York, NY, 10029, USA.
Michael S TorbensonDepartment of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Michael L WellsDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Benjamin YehDepartment of Radiology and Biomedical Imaging, UCSF School of Medicine, Zuckerberg San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA, 94110, USA.
Frank H MillerDepartment of Radiology, Feinberg School of Medicine, Northwestern University, 676 St. Clair St, Suite 800, Chicago, IL, 60611, USA.
Mayo Clinic · USNorthwestern University · USSan Francisco General Hospital · USIcahn School of Medicine at Mount Sinai · USMassachusetts General Hospital · USMayo Clinic in Arizona · USWomen's College Hospital · CA

Funding

Magnetic Resonance ElastographyR37EB001981 · NIBIB · MAYO CLINIC ROCHESTER · PI EHMAN, RICHARD L. · 2016 to 2025
$4.0M
Reducing Variability in Hepatic Shear Wave ElastographyK23EB020710 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI SAMIR, ANTHONY EDWARD · 2016 to 2019
$781k
NIBIB NIH HHS K23 EB020710NIBIB NIH HHS R37 EB001981
6 · The paper itself

Abstract

Hepatic fibrosis is potentially reversible; however early diagnosis is necessary for treatment in order to halt progression to cirrhosis and development of complications including portal hypertension and hepatocellular carcinoma. Morphologic signs of cirrhosis on ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) alone are unreliable and are seen with more advanced disease. Newer imaging techniques to diagnose liver fibrosis are reliable and accurate, and include magnetic resonance elastography and US elastography (one-dimensional transient elastography and point shear wave elastography or acoustic radiation force impulse imaging). Research is ongoing with multiple other techniques for the noninvasive diagnosis of hepatic fibrosis, including MRI with diffusion-weighted imaging, hepatobiliary contrast enhancement, and perfusion; CT using perfusion, fractional extracellular space techniques, and dual-energy, contrast-enhanced US, texture analysis in multiple modalities, quantitative mapping, and direct molecular imaging probes. Efforts to advance the noninvasive imaging assessment of hepatic fibrosis will facilitate earlier diagnosis and improve patient monitoring with the goal of preventing the progression to cirrhosis and its complications.

Indexed as

Contrast MediaEarly DiagnosisHumansImage Interpretation, Computer-AssistedLiver CirrhosisContrast MediaChronic liver diseaseElastographyFibrosisMagnetic resonance imagingPerfusionSonography

Identifiers

PMID28624924
PMCPMC5994771
OpenAlexW2625075605

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.