Evidence map›Paper›PMID 28624867›Full record

ReviewGeroScience2017

Cytomegalovirus (CMV) research in immune senescence comes of age: overview of the 6th International Workshop on CMV and Immunosenescence.

Janko Nikolich-Žugich, René A W van Lier

Open access · bronzeAbstract readEditorialReview
In one paragraph

Review in GeroScience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 56 citations in OpenAlex.

  1. Trial
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  3. Seroprevalence of human cytomegalovirus in blood donors.GMS hygiene and infection control · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Janko Nikolich-ŽugichDepartment of Immunobiology and the Arizona Center on Aging, College of Medicine, University of Arizona, Tucson, AZ, 85724, USA. nikolich@email.arizona.edu.ORCID 0000-0001-5830-5323
René A W van LierSanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Amsterdam UMC Location University of Amsterdam · NLUniversity of Arizona · US

Funding

Research Supplement to Impact on CMV Upon T-Cell Aging and Immune DefenseR01AG048021 · NIA · UNIVERSITY OF ARIZONA · PI NIKOLICH, JANKO Z. · 2014 to 2018
$2.6M
NIA NIH HHS R01 AG048021
6 · The paper itself

Abstract

Cytomegalovirus (CMV) is one of the most complex and most ubiquitous latent persistent viruses, with a considerable ability to evade and manipulate the immune system. Following an early-life infection, most immunocompetent humans spend several decades living with CMV, and, because the virus in these hosts does not cause manifest disease, CMV can be considered part of normal aging for more than half of humanity. However, there is accumulating evidence that CMV carriage is not a null event and that both potentially harmful and potentially beneficial outcomes emanate from the interaction of CMV with its mammalian hosts. This article provides an overview of the 6th International Workshop on CMV and Immunosenescence, highlighting the advances in the field made in the past two years, as related to CMV epidemiology/geroscience, CMV virology with an accent on latency, and CMV immune evasion and immune recognition of the virus and its antigens.

Indexed as

GeriatricsImmunosenescenceAgingArizonaCongresses as TopicCytomegalovirusCytomegalovirus InfectionsHumansVirus LatencyCytomegalovirusImmunosenescenceInflammationT cells

Identifiers

PMID28624867
PMCPMC5505886
OpenAlexW2626351472

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.