ArticleJournal of theoretical biology2017
Endosymbiosis: The feeling is not mutual.
Article in Journal of theoretical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed.
- Genomic Evolution of Francisella: Metabolic Innovation, Endosymbiotic Transitions to Ticks, and Biogeographic History.Genome biology and evolution · 2026Article
- The bacterial march toward symbiosis: on-ramps and off-ramps.Trends in microbiology · 2026Review
- Volume electron microscopy reveals bacterial endosymbiosis within host mitochondria.Communications biology · 2026Article
- Comparative Genomics Reveals Multipartite Genomes Undergoing Loss in the Fungal Endosymbiotic Genus Mycetohabitans.Genome biology and evolution · 2025Article
- Induced endosymbiosis between a fungus and bacterium reveals a shift from antagonism to commensalism.Nature communications · 2025Article
- Tracing the evolutionary pathway: on the origin of mitochondria and eukaryogenesis.The FEBS journal · 2025Article
- A diverse Palaeoproterozoic microbial ecosystem implies early eukaryogenesis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Article
- Relationship troubles at the mitochondrial level and what it might mean for human disease.Open biology · 2025Review
- Adaptation During the Shift from Entomopathogen to Endosymbiont Is Accompanied by Gene Loss and Intensified Selection.Genome biology and evolution · 2024Article
- Complex third-party effects in theProceedings. Biological sciences · 2024Article
- Symbiosis: In search of a deeper understanding.PLoS biology · 2024Article
- Symbiotic revolutions at the interface of genomics and microbiology.PLoS biology · 2024Article
- Modeling endosymbioses: Insights and hypotheses from theoretical approaches.PLoS biology · 2024Article
- Cross-validation of chemical and genetic disruption approaches to inform host cellular effects onFrontiers in microbiology · 2024Article
- A theoretical model for host-controlled regulation of symbiont density.Journal of evolutionary biology · 2023Article
- High-throughput identification of Toxoplasma gondii effector proteins that target host cell transcription.Cell host & microbe · 2023Article
- How It All Begins: Bacterial Factors Mediating the Colonization of Invertebrate Hosts by Beneficial Symbionts.Microbiology and molecular biology reviews : MMBR · 2022Review
- Evolution of manipulative microbial behaviors in the rhizosphere.Evolutionary applications · 2022Review
- Context dependence in the symbiosis betweenEvolution letters · 2022Article
- Organellar Evolution: A Path from Benefit to Dependence.Microorganisms · 2022Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Endosymbiosis is an idea that provided a remarkable amount of explanatory power about the origins of eukaryotic organelles. But it also promoted a number of assumptions that have also been influential, but are less well-examined. Here we look at two of these to see whether or not they fit current evidence. The assumption we first address is that endosymbiotic relationships such as nutritional symbioses and eukaryotic organelles are mutualisms. We argue instead that they are more one-sided associations that can be regarded as context-dependent power struggles like any other ecological interaction. The second assumption is that during endosymbiotic interactions (such as the origin of organelles), the host genomes will acquire a great many genes from endosymbionts that assume functions in host systems (as opposed to the well-documented genes whose products are simply targeted back to the endosymbiont or organelle). The idea that these genes exist in large numbers has been influential in a number of hypotheses about organelle evolution and distribution, but in the most carefully-examined systems no such mass migration of genes is evident. Overall, we argue that both the nature and impact of endosymbiosis need to be constantly re-evaluated to fully understand what roles it really plays in both cell biology and evolution.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.