ArticleCritical care (London, England)2017
Hemoglobin concentrations and RBC transfusion thresholds in patients with acute brain injury: an international survey.
Article in Critical care (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Red blood cell transfusion strategy in traumatic brain injury patients: a systematic review and meta-analysis.European journal of medical research · 2025Pooled it
- Red blood cell transfusion in neurocritical patients: a systematic review and meta-analysis.BMC anesthesiology · 2024Pooled it
- Trial
- Transfusion requirements after head trauma: a randomized feasibility controlled trial.Critical care (London, England) · 2019Trial
- Early hemoglobin trajectories and short-term mortality in ICU patients with traumatic brain injury: development in MIMIC-IV and external assessment in eICU-CRD.Frontiers in neurology · 2026Observational
- Article
- Cerebral oxygen saturation in cirrhotic patients with gastro-intestinal bleeding, a near infrared spectroscopy study.Metabolic brain disease · 2025Article
- Association of hemoglobin drift and outcomes in patients with aneurysmal subarachnoid hemorrhage.Neurosurgical review · 2024Article
- Haemoglobin values, transfusion practices, and long-term outcomes in critically ill patients with traumatic brain injury: a secondary analysis of CENTER-TBI.Critical care (London, England) · 2024Observational
- Hematocrit drift and outcomes in surgical patients with aneurysmal subarachnoid hemorrhage.Acta neurochirurgica · 2024Article
- Article
- Perioperative Management of Polytrauma Patients with Severe Traumatic Brain Injury Undergoing Emergency Extracranial Surgery: A Narrative Review.Journal of clinical medicine · 2021Review
- Aneurysmal Subarachnoid Hemorrhage: the Last Decade.Translational stroke research · 2021Review
- Critical Care Society of Southern Africa adult patient blood management guidelines: 2019 Round-table meeting, CCSSA Congress, Durban, 2018.The Southern African journal of critical care : the official journal of the Critical Care Society · 2020Article
- Transfusion practices in traumatic brain injury.Current opinion in anaesthesiology · 2018Review
- Cerebral Microdialysis Monitoring to Improve Individualized Neurointensive Care Therapy: An Update of Recent Clinical Data.Frontiers in neurology · 2017Review
- Liberal versus restrictive transfusion strategies in patients with acute brain injury: a systematic review and meta-analysis of randomized controlled trials.Proceedings (Baylor University. Medical Center)Article
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe optimal hemoglobin (Hb) threshold at which to initiate red blood cell (RBC) transfusion in patients with acute brain injury is unknown. The aim of this survey was to investigate RBC transfusion practices used with these patients.
methodsWe conducted a web-based survey within various societies of critical care medicine for intensive care unit (ICU) physicians who currently manage patients with primary acute brain injury.
resultsA total of 868 responses were obtained from around the world, half of which (n = 485) were from European centers; 204 (24%) respondents had a specific certificate in neurocritical care, and most were specialists in anesthesiology or intensive care and had less than 15 years of practice experience. Four hundred sixty-six respondents (54%) said they used an Hb threshold of 7-8 g/dl to initiate RBC transfusion after acute brain injury, although half of these respondents used a different threshold (closer to 9 g/dl) in patients with traumatic brain injury, subarachnoid hemorrhage, or ischemic stroke. Systemic and cerebral factors were reported as influencing the need for higher Hb thresholds. Most respondents agreed that a randomized clinical trial was needed to compare two different Hb thresholds for RBC transfusion, particularly in patients with traumatic brain injury, subarachnoid hemorrhage, and ischemic stroke.
conclusionsThe Hb threshold used for RBC transfusion after acute brain injury was less than 8 g/dl in half of the ICU clinicians who responded to our survey. However, more than 50% of these physicians used higher Hb thresholds in certain conditions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.