ArticleBMC anesthesiology2017
Systolic blood pressure variability in patients with early severe sepsis or septic shock: a prospective cohort study.
Article in BMC anesthesiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Blood pressure variability and its utility in acute disease and critical illness: a systematic review.BMC anesthesiology · 2025Pooled it
- Risk factors for chronic kidney disease and septic shock with hypertension in adults and children.Frontiers in nephrology · 2025Pooled it
- Sex differences in blood pressure variability during critical illness: a retrospective cohort study.Open heart · 2026Article
- The impacts of blood pressure variability on clinical outcomes in patients with out-of-hospital cardiac arrest.Resuscitation plus · 2025Article
- The additive effect of glycemic variability and systolic blood pressure variability on mortality in patients with sepsis.BMC infectious diseases · 2025Article
- Advancing shock prediction: leveraging prior knowledge and self-controlled data for enhanced model accuracy and generalizability.BMC medical informatics and decision making · 2025Article
- Intelligent Prediction Platform for Sepsis Risk Based on Real-Time Dynamic Temporal Features: Design Study.JMIR medical informatics · 2025Article
- Comprehensive Sepsis Risk Prediction in Leukemia Using a Random Forest Model and Restricted Cubic Spline Analysis.Journal of inflammation research · 2025Article
- Cardiovascular Autonomic Dysfunction in Hospitalized Patients with a Bacterial Infection: A Longitudinal Observational Pilot Study in the UK.Biomedicines · 2024Article
- Association of Blood Pressure Variability With Death and Discharge Destination Among Critically Ill Patients With and Without Stroke.Neurology · 2023Article
- Observational
- Evaluation of SI, MSI and DSI for very early (3-day) mortality in patients with septic shock.European journal of medical research · 2022Article
- Influence of ambulatory blood pressure-related indicators within 24 h on in-hospital death in sepsis patients.International journal of medical sciences · 2022Article
- Cerebral Autoregulation-Guided Optimal Blood Pressure in Sepsis-Associated Encephalopathy: A Case Series.Journal of intensive care medicine · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundSevere sepsis and septic shock are often lethal syndromes, in which the autonomic nervous system may fail to maintain adequate blood pressure. Heart rate variability has been associated with outcomes in sepsis. Whether systolic blood pressure (SBP) variability is associated with clinical outcomes in septic patients is unknown. The propose of this study is to determine whether variability in SBP correlates with vasopressor independence and mortality among septic patients.
methodsWe prospectively studied patients with severe sepsis or septic shock, admitted to an intensive care unit (ICU) with an arterial catheter. We analyzed SBP variability on the first 5-min window immediately following ICU admission. We performed principal component analysis of multidimensional complexity, and used the first principal component (PC
resultsWe studied 51 patients, 51% of whom achieved vasopressor independence at 24 h. Ten percent died at 28 days. PC
conclusionsEarly SBP variability appears to be associated with 28-day mortality in patients with severe sepsis and septic shock.
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