Evidence map›Paper›PMID 28623880›Full record

Observational studyAddiction (Abingdon, England)2017

Associations between anhedonia and marijuana use escalation across mid-adolescence.

Adam M Leventhal, Junhan Cho, Matthew D Stone, Jessica L Barrington-Trimis, Chih-Ping Chou, Steven Y Sussman, Nathaniel R Riggs, Jennifer B Unger, Janet Audrain-McGovern, David R Strong

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Addiction (Abingdon, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 89 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Adam M LeventhalDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Junhan ChoDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Matthew D StoneDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Jessica L Barrington-TrimisDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Chih-Ping ChouDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Steven Y SussmanDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Nathaniel R RiggsDepartment of Human Development and Family Studies, Colorado State University, Fort Collins, CO, USA.
Jennifer B UngerDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Janet Audrain-McGovernDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
David R StrongDepartment of Family Medicine and Public Health, School of Medicine, University of California, San Diego, La Jolla, CA, USA.
University of Southern California · USColorado State University · USUniversity of California, San Diego · USUniversity of Pennsylvania · US

Funding

USC Tobacco Center of Regulatory Science (TCORS) for Vulnerable PopulationsP50CA180905 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PENTZ, MARY ANN, SAMET, JONATHAN M · 2013 to 2017
$20.1M
Anhedonia as a Risk Factor and Consequence of Substance UseR01DA033296 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LEVENTHAL, ADAM MATTHEW · 2012 to 2016
$3.4M
NCI NIH HHS P50 CA180905NIDA NIH HHS R01 DA033296
6 · The paper itself

Abstract

BACKGROUND AND

aimsAnhedonia-a transdiagnostic psychopathological trait indicative of inability to experience pleasure-could lead to and result from adolescent marijuana use, yet this notion has not been tested. This study aimed to estimate the association of: (1) anhedonia at age 14 with rate of change in marijuana use over an 18-month follow-up, and (2) marijuana use at age 14 with rate of change in anhedonia over follow-up. Secondary aims were to test whether gender, baseline marijuana use history and peer marijuana use moderated these associations.

designObservational longitudinal cohort repeated-measures design, with baseline (age 14 years), 6-month, 12-month and 18-month follow-up assessments. SETTINGS: Ten public high schools in Los Angeles, CA, USA, 2013-15.

participantsStudents [n = 3394; 53.5% female, mean (standard deviation) age at baseline = 14.1 (0.42)]. MEASUREMENTS: Self-report level of anhedonia on the Snaith-Hamilton Pleasure Scale and frequency of marijuana use in the past 30 days.

findingsParallel process latent growth curve models adjusting for confounders showed that baseline anhedonia level was associated positively with the rate of increase in marijuana use frequency across follow-ups [β, 95% confidence interval (CI) = 0.115 (0.022, 0.252), P = 0.03]. Baseline marijuana use frequency was not related significantly to the rate of change in anhedonia across follow-ups [β, 95% CI = -0.015 (-0.350, 0.321), P = 0.93]. The association of baseline anhedonia with faster marijuana use escalation was amplified among adolescents with (versus without) friends who used marijuana at baseline [β, 95% CI = 0.179 (0.043, 0.334) versus 0.064 (-0.071, 0.187), interaction P = 0.04], but did not differ by gender or baseline ever marijuana use.

conclusionsIn mid-adolescence, anhedonia is associated with subsequent marijuana use escalation, but marijuana use escalation does not appear to be associated with subsequent anhedonia.

Indexed as

AdolescentAdolescent BehaviorAnhedoniaCohort StudiesFemaleHumansLongitudinal StudiesLos AngelesMaleMarijuana UseSelf ReportAdolescentsanhedonialongitudinal researchmarijuana usepolicyprevention

Identifiers

PMID28623880
PMCPMC5673572
OpenAlexW2626840143

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.