Evidence map›Paper›PMID 28623610›Full record

ArticleStem cell reviews and reports2017

A Singular Role of I

Yu Sun, Valeriy Timofeyev, Adrienne Dennis, Emre Bektik, Xiaoping Wan, Kenneth R Laurita, Isabelle Deschênes, Ronald A Li, Ji-Dong Fu

Open access · greenAbstract read
In one paragraph

Article in Stem cell reviews and reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
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  8. Multilayer control of cardiac electrophysiology by microRNAs.Journal of molecular and cellular cardiology · 2022
    Review
  9. Article
  10. Article
  11. Article
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  13. Review
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  15. Article
  16. Kir2 inward rectification-controlled precise and dynamic balances between Kir2 and HCN currents initiate pacemaking activity.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 5 countries.

Yu SunDepartment of Medicine, Heart and Vascular Research Center, MetroHealth Campus, Case Western Reserve University, 2500 Metrohealth Drive, Rammelkamp 650, Cleveland, OH, 44109, USA.
Valeriy TimofeyevDepartment of Internal Medicine, University of California, Davis, CA, USA.
Adrienne DennisDepartment of Medicine, Heart and Vascular Research Center, MetroHealth Campus, Case Western Reserve University, 2500 Metrohealth Drive, Rammelkamp 650, Cleveland, OH, 44109, USA.
Emre BektikDepartment of Medicine, Heart and Vascular Research Center, MetroHealth Campus, Case Western Reserve University, 2500 Metrohealth Drive, Rammelkamp 650, Cleveland, OH, 44109, USA.
Xiaoping WanDepartment of Medicine, Heart and Vascular Research Center, MetroHealth Campus, Case Western Reserve University, 2500 Metrohealth Drive, Rammelkamp 650, Cleveland, OH, 44109, USA.
Kenneth R LauritaDepartment of Medicine, Heart and Vascular Research Center, MetroHealth Campus, Case Western Reserve University, 2500 Metrohealth Drive, Rammelkamp 650, Cleveland, OH, 44109, USA.
Isabelle DeschênesDepartment of Medicine, Heart and Vascular Research Center, MetroHealth Campus, Case Western Reserve University, 2500 Metrohealth Drive, Rammelkamp 650, Cleveland, OH, 44109, USA.
Ronald A LiDr. Li Dak-Sum Center for Regenerative Medicine, University of Hong Kong, The Hong Kong Jockey Club Building for Interdisciplinary Research, LB 5-06, 5 Sassoon Road, Pokfulam, Hong Kong. ronaldli@hku.hk.
Ji-Dong FuDepartment of Medicine, Heart and Vascular Research Center, MetroHealth Campus, Case Western Reserve University, 2500 Metrohealth Drive, Rammelkamp 650, Cleveland, OH, 44109, USA. jidong.fu@case.edu.ORCID 0000-0003-2797-5193
MetroHealth Medical Center · USScience for Life Laboratory · SEUniversity of California, Davis · USUniversity of Tsukuba · JP

Funding

Cardiac Ion Channel RegulationR01HL096962 · NHLBI · OHIO STATE UNIVERSITY · PI DESCHENES, ISABELLE, TSENG, GEA-NY · 2010 to 2021
$3.6M
Fully optical high throughput screening platform for drug induced arrhythmiasR21HL123012 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI LAURITA, KENNETH · 2015 to 2016
$436k
American Heart Association 13SDG14580035NHLBI NIH HHS R01 HL096962NHLBI NIH HHS R01HL096962NHLBI NIH HHS R21 HL123012NHLBI NIH HHS R21HL123012Research Grants Council, University Grants Committee TRA T13-706/11
6 · The paper itself

Abstract

The inward rectifier potassium current (I

Indexed as

PeriodicityAction PotentialsAdenoviridaeAnimalsBenzamidesBridged Bicyclo Compounds, HeterocyclicCell DifferentiationCell LineEmbryonic Stem CellsGene ExpressionGenetic VectorsHEK293 CellsHumansHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsLentivirusMiceBenzamidesBridged Bicyclo Compounds, HeterocyclicHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsKir2.1 channelPotassium Channels, Inwardly RectifyingzacoprideAutomaticityCardiomyocyte differentiationEmbryonic stem cellIfIK1Rhythmic oscillation

Identifiers

PMID28623610
PMCPMC5784831
OpenAlexW2626510561

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.