Evidence map›Paper›PMID 28623514›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2018

The potential roles of bacteria to improve radiation treatment outcome.

E Kouhsari, A Ghadimi-Daresajini, H Abdollahi, N Amirmozafari, S R Mahdavi, S Abbasian, S H Mousavi, H F Yaseri, M Moghaderi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
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  7. Review
  8. New physical approaches to treat cancer stem cells: a review.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

E KouhsariDepartment of Medical Bacteriology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
A Ghadimi-DaresajiniDepartment of Medical Biotechnology, Faculty of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran.
H AbdollahiDepartment of Medical Physics, School of Medicine, Iran University of Medical Sciences, Shahid Hemmat and Shahid Chamran Expressways, Tehran, 14496-14535, Iran. hamid_rbp@yahoo.com.ORCID http://orcid.org/0000-0003-0761-1309
N AmirmozafariDepartment of Medical Bacteriology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
S R MahdaviDepartment of Medical Physics, School of Medicine, Iran University of Medical Sciences, Shahid Hemmat and Shahid Chamran Expressways, Tehran, 14496-14535, Iran.
S AbbasianDepartment of Medical Bacteriology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
S H MousaviDepartment of General Surgery, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
H F YaseriResearch Center for Gastroenterology and Liver Disease, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
M MoghaderiDepartment of Traditional Medicine, School of Traditional Medicine, Kerman University of Medical Sciences, Kerman, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many combined therapies have been proposed to enhance radiotherapy outcome, but they have several limitations. As a new feasible strategy, combination of radiotherapy with bacteria showed a significant positive impact on the tumor treatment and metastasis inhibition. Although probiotic bacteria and radiotherapy alone can be effective in the treatment of different cancers, the combination of these two therapies seems to enhance therapeutic outcome and is cost-effective. Bacterial cells can act as therapeutic/gene/drug delivery vehicles as well as theranostic agents. In this communication, we reviewed current evidences, studies, suggestions, and future-based directions on combination of radiotherapy and bacteria. In another sections, an overview on tumor hypoxia, bacteria in cancer therapy, and combination of radiotherapy and bacteria is presented. A brief overview on trials and animal studies which used bacteria to protect normal tissues against radiotherapy-induced complications is also included.

Indexed as

Drug Delivery SystemsRadiotherapyBacteriaCombined Modality TherapyHumansNeoplasmsProbioticsTreatment OutcomeBacteriaOutcomeRadioprotectorRadiosensitizerRadiotherapyTheranostic

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.