ArticleEnvironmental geochemistry and health2018
Blood concentrations of lead, cadmium, mercury and their association with biomarkers of DNA oxidative damage in preschool children living in an e-waste recycling area.
Article in Environmental geochemistry and health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 92 citations in OpenAlex.
- A systematic review of the health effects of lead exposure from electronic waste in children.Frontiers in public health · 2023Pooled it
- Systematic Review and Meta-Analysis of Mercury Exposure among Populations and Environments in Contact with Electronic Waste.International journal of environmental research and public health · 2022Pooled it
- Health consequences of exposure to e-waste: an updated systematic review.The Lancet. Planetary health · 2021Pooled it
- The association between body lead levels and childhood rickets: A meta-analysis based on Chinese cohort.Medicine · 2019Pooled it
- Tracing the threads: How toxic metals contribute to neurodegeneration.IBRO neuroscience reports · 2026Review
- Tattoo Ink Exposure and Its Potential Link with Lymphoma and Skin Cancer: A Narrative Review of New Evidence.Cardiovascular & hematological disorders drug targets · 2026Review
- As, Cd, Hg, and Pb Biological Concentrations and Anthropometry in Slovak Adolescents.Biological trace element research · 2025Article
- E-waste: mechanisms of toxicity and safety testing.FEBS open bio · 2024Review
- Toxicological Aspects Associated with Consumption from Electronic Nicotine Delivery System (ENDS): Focus on Heavy Metals Exposure and Cancer Risk.International journal of molecular sciences · 2024Review
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- Review
- Metabolic diseases and healthy aging: identifying environmental and behavioral risk factors and promoting public health.Frontiers in public health · 2023Review
- Metabolic and genetic derangement: a review of mechanisms involved in arsenic and lead toxicity and genotoxicity.Arhiv za higijenu rada i toksikologiju · 2022Review
- Genotoxic Biomonitoring in Children Living near the El Fraile Mine Tailings in Northern Guerrero State, Mexico.Toxics · 2022Article
- Ecological Burden of e-Waste in Bangladesh-an Assessment to Measure the Exposure to e-Waste and Associated Health Outcomes: Protocol for a Cross-sectional Study.JMIR research protocols · 2022Article
- Genotoxic Effects of Lead and Their Impact on the Expression of DNA Repair Genes.International journal of environmental research and public health · 2022Review
- Bioremediation potential ofBiotechnology reports (Amsterdam, Netherlands) · 2021Article
- Human Body Burden of Heavy Metals and Health Consequences of Pb Exposure in Guiyu, an E-Waste Recycling Town in China.International journal of environmental research and public health · 2021Review
- Bibliometric analysis of studies involving e-waste: a critical review.Environmental science and pollution research international · 2021Review
- E-Waste in Africa: A Serious Threat to the Health of Children.International journal of environmental research and public health · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Reactive oxygen species (ROS)-induced DNA damage occurs in heavy metal exposure, but the simultaneous effect on DNA repair is unknown. We investigated the influence of co-exposure of lead (Pb), cadmium (Cd), and mercury (Hg) on 8-hydroxydeoxyguanosine (8-OHdG) and human repair enzyme 8-oxoguanine DNA glycosylase (hOGG1) mRNA levels in exposed children to evaluate the imbalance of DNA damage and repair. Children within the age range of 3-6 years from a primitive electronic waste (e-waste) recycling town were chosen as participants to represent a heavy metal-exposed population. 8-OHdG in the children's urine was assessed for heavy metal-induced oxidative effects, and the hOGG1 mRNA level in their blood represented the DNA repair ability of the children. Among the children surveyed, 88.14% (104/118) had a blood Pb level >5 μg/dL, 22.03% (26/118) had a blood Cd level >1 μg/dL, and 62.11% (59/95) had a blood Hg level >10 μg/dL. Having an e-waste workshop near the house was a risk factor contributing to high blood Pb (r
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.