Evidence map›Paper›PMID 28623182›Full record

ArticleJournal of medical Internet research2017

MyGeneFriends: A Social Network Linking Genes, Genetic Diseases, and Researchers.

Alexis Allot, Kirsley Chennen, Yannis Nevers, Laetitia Poidevin, Arnaud Kress, Raymond Ripp, Julie Dawn Thompson, Olivier Poch, Odile Lecompte

Open access · goldAbstract read
In one paragraph

Article in Journal of medical Internet research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Alexis AllotICUBE UMR 7357, Complex Systems and Translational Bioinformatics, Université de Strasbourg - CNRS - FMTS, Strasbourg, France.ORCID 0000-0002-2706-9054
Kirsley ChennenICUBE UMR 7357, Complex Systems and Translational Bioinformatics, Université de Strasbourg - CNRS - FMTS, Strasbourg, France.ORCID 0000-0001-9268-6748
Yannis NeversICUBE UMR 7357, Complex Systems and Translational Bioinformatics, Université de Strasbourg - CNRS - FMTS, Strasbourg, France.ORCID 0000-0002-8604-2943
Laetitia PoidevinICUBE UMR 7357, Complex Systems and Translational Bioinformatics, Université de Strasbourg - CNRS - FMTS, Strasbourg, France.ORCID 0000-0002-6750-3732
Arnaud KressICUBE UMR 7357, Complex Systems and Translational Bioinformatics, Université de Strasbourg - CNRS - FMTS, Strasbourg, France.ORCID 0000-0002-7616-8876
Raymond RippICUBE UMR 7357, Complex Systems and Translational Bioinformatics, Université de Strasbourg - CNRS - FMTS, Strasbourg, France.ORCID 0000-0003-3766-0013
Julie Dawn ThompsonICUBE UMR 7357, Complex Systems and Translational Bioinformatics, Université de Strasbourg - CNRS - FMTS, Strasbourg, France.ORCID 0000-0003-4893-3478
Olivier PochICUBE UMR 7357, Complex Systems and Translational Bioinformatics, Université de Strasbourg - CNRS - FMTS, Strasbourg, France.ORCID 0000-0002-7134-3217
Odile LecompteICUBE UMR 7357, Complex Systems and Translational Bioinformatics, Université de Strasbourg - CNRS - FMTS, Strasbourg, France.ORCID 0000-0002-2005-460X
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe constant and massive increase of biological data offers unprecedented opportunities to decipher the function and evolution of genes and their roles in human diseases. However, the multiplicity of sources and flow of data mean that efficient access to useful information and knowledge production has become a major challenge. This challenge can be addressed by taking inspiration from Web 2.0 and particularly social networks, which are at the forefront of big data exploration and human-data interaction.

objectiveMyGeneFriends is a Web platform inspired by social networks, devoted to genetic disease analysis, and organized around three types of proactive agents: genes, humans, and genetic diseases. The aim of this study was to improve exploration and exploitation of biological, postgenomic era big data.

methodsMyGeneFriends leverages conventions popularized by top social networks (Facebook, LinkedIn, etc), such as networks of friends, profile pages, friendship recommendations, affinity scores, news feeds, content recommendation, and data visualization.

resultsMyGeneFriends provides simple and intuitive interactions with data through evaluation and visualization of connections (friendships) between genes, humans, and diseases. The platform suggests new friends and publications and allows agents to follow the activity of their friends. It dynamically personalizes information depending on the user's specific interests and provides an efficient way to share information with collaborators. Furthermore, the user's behavior itself generates new information that constitutes an added value integrated in the network, which can be used to discover new connections between biological agents.

conclusionsWe have developed MyGeneFriends, a Web platform leveraging conventions from popular social networks to redefine the relationship between humans and biological big data and improve human processing of biomedical data. MyGeneFriends is available at lbgi.fr/mygenefriends.

Indexed as

Social NetworkingFriendsGenetic Diseases, InbornGenetic TestingHumansResearch PersonnelTelemedicinegenetic variationhealth carehereditary diseasesocial media

Identifiers

PMID28623182
PMCPMC5493784
OpenAlexW2625713191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.