Evidence map›Paper›PMID 28622956›Full record

Trial reportThe Journal of pediatrics2017

Obesity, Visceral Adipose Tissue, and Cognitive Function in Childhood.

Lauren B Raine, Naiman A Khan, Eric S Drollette, Matthew B Pontifex, Arthur F Kramer, Charles H Hillman

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01334359 phase3completednot on this map

ERPs to Academics: Exercise Effects on Cognition in School-Aged Children

TypeinterventionalSponsorUniversity of Illinois at Urbana-ChampaignRan2008 to 2012Enrolled252ConditionsBrain Health, Cognition, Scholastic AchievementArmsPhysical Activity
NCT01619826 nacompletednot on this map

Enhancing Children's Cognitive and Brain Health Through Physical Activity Training

TypeinterventionalSponsorUniversity of Illinois at Urbana-ChampaignRan2012 to 2017Enrolled300ConditionsCognitive Ability, General, AchievementArmsPhysical Activity
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Interventions to prevent obesity in children aged 5 to 11 years old.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Interventions for preventing obesity in children.The Cochrane database of systematic reviews · 2019
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lauren B RaineDepartment of Psychology, Northeastern University, Boston, MA. Electronic address: l.raine@northeastern.edu.
Naiman A KhanDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Champaign, IL.
Eric S DrolletteDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Champaign, IL.
Matthew B PontifexDepartment of Kinesiology, Michigan State University, East Lansing, MI.
Arthur F KramerDepartment of Psychology, Northeastern University, Boston, MA; Beckman Institute, University of Illinois at Urbana-Champaign, Champaign, IL.
Charles H HillmanDepartment of Psychology, Northeastern University, Boston, MA; Department of Health Science, Northeastern University, Boston, MA.

Funding

Enhancing Child Cognitive and Brain Health through Physical Activity TrainingR01HD069381 · NICHD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI MCAULEY, EDWARD · 2012 to 2016
$3.0M
ERPs to Academics: Exercise Effects on Cognition in School-Aged ChildrenR01HD055352 · NICHD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI HILLMAN, CHARLES H · 2008 to 2011
$1.3M
NICHD NIH HHS R01 HD055352NICHD NIH HHS R01 HD069381
6 · The paper itself

Abstract

objectivesTo evaluate the effects of a 9-month physical activity intervention on changes in adiposity and cognitive control based on pretrial weight status (ie, healthy weight vs obese) in children. STUDY

designParticipants included obese (n = 77) and matched healthy-weight (n = 77) preadolescents (8-9 years) who participated in a 9-month physical activity randomized controlled trial. Cognitive function was assessed with an inhibitory control task (modified flanker task).

resultsAfter the 9-month physical activity intervention, participants exhibited a reduction in adiposity. In contrast, children in the waitlist-control condition, particularly children identified as obese pretrial, gained visceral adipose tissue (P= .008). Changes in visceral adipose tissue were related to changes in cognitive performance, such that the degree of reduction in visceral adipose tissue directly related to greater gains in inhibitory control, particularly among obese intervention participants (CI -0.14, -0.04; P= .001).

conclusionsParticipation in a daily physical activity program not only reduces adiposity but also improves children's cognitive function as demonstrated by an inhibitory control task. Furthermore, these findings reveal that the benefits of physical activity to improvements in cognitive function are particularly evident among children who are obese.

trial registrationClinicalTrials.gov: NCT01334359 and NCT01619826.

Indexed as

CognitionAdiposityBody WeightChildExerciseFemaleHumansIntra-Abdominal FatMalePediatric ObesityWeight Lossadiposityinhibitory controlphysical activity

Identifiers

PMID28622956
PMCPMC5541384

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.