ArticleMuscle & nerve2018
Ultrasound-guided hydrodissection decreases gliding resistance of the median nerve within the carpal tunnel.
Article in Muscle & nerve, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 38 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Clinical Volume Effect of Nerve Hydrodissection in Patients With Carpal Tunnel Syndrome
Comparison of the Efficacy of Ultrasound-Guided Median Nerve Hydrodissection With Dexamethasone and Dextrose at Different Volumes in Patients With Carpal Tunnel Syndrome: A Prospective, Randomized, Double Blind Study
Who cites it
38 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Ultrasound-Guided Nerve Hydrodissection for the Management of Carpal Tunnel Syndrome: A Systematic Review and Network Meta-Analysis.Yonsei medical journal · 2025Pooled it
- Local corticosteroid injection versus surgery for carpal tunnel syndrome.The Cochrane database of systematic reviews · 2024Pooled it
- Impaired median nerve mobility in patients with carpal tunnel syndrome: a systematic review and meta-analysis.European radiology · 2023Pooled it
- Local corticosteroid injection versus placebo for carpal tunnel syndrome.The Cochrane database of systematic reviews · 2023Pooled it
- Local injection therapy for carpal tunnel syndrome: a network meta-analysis of randomized controlled trial.Frontiers in pharmacology · 2023Pooled it
- Pooled it
- Volume Matters in Ultrasound-Guided Perineural Dextrose Injection for Carpal Tunnel Syndrome: A Randomized, Double-Blinded, Three-Arm Trial.Frontiers in pharmacology · 2020Trial
- Non-Biologic Injections in Sports Medicine.Current reviews in musculoskeletal medicine · 2026Review
- Improved range of motion in three cases following axillary nerve hydrorelease after reverse shoulder arthroplasty: a case series.Journal of orthopaedic case reports · 2026Article
- Common Fascial Abnormalities in Five Thumb Pain Conditions: A Fifteen-Point Ultrasound-Guided Fascia Hydrorelease Clinical Protocol.Journal of functional morphology and kinesiology · 2026Article
- Review
- Review
- Hydrorelease Within the Paraneural Sheath: A Cadaveric Study.Journal of functional morphology and kinesiology · 2026Article
- Ultrasound-guided hydrorelease/hydrodissection reduces gliding resistance in a rat sciatic nerve adhesion model : a preclinical experimental study.Journal of orthopaedic surgery and research · 2026Article
- Review
- The Effectiveness of Ultrasound-Guided Glucose Combined with Mecobalamin Neurolysis in Treating Patients with Refractory Painful Peripheral Neuropathy Using the DCEC Ultrasound Score: A Retrospective Study.Journal of pain research · 2026Article
- Article
- Article
- Article
- Ultrasound-Guided Fascial Hydrorelease for Persistent Pain After Hamstring Injury.Journal of functional morphology and kinesiology · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
introductionThe aim of this study was to assess alterations in median nerve (MN) biomechanics within the carpal tunnel resulting from ultrasound-guided hydrodissection in a cadaveric model.
methodsTwelve fresh frozen human cadaver hands were used. MN gliding resistance was measured at baseline and posthydrodissection, by pulling the nerve proximally and then returning it to the origin. Six specimens were treated with hydrodissection, and 6 were used as controls.
resultsIn the hydrodissection group there was a significant reduction in mean peak gliding resistance of 92.9 ± 34.8 mN between baseline and immediately posthydrodissection (21.4% ± 10.5%; P = 0.001). No significant reduction between baseline and the second cycle occurred in the control group: 9.6 ± 29.8 mN (0.4% ± 5.3%; P = 0.467). DISCUSSION: Hydrodissection can decrease the gliding resistance of the MN within the carpal tunnel, at least in wrists unaffected by carpal tunnel syndrome. A clinical trial of hydrodissection seems justified. Muscle Nerve 57: 25-32, 2018.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.