ArticlePLoS neglected tropical diseases2017
Minimal genetic change in Vibrio cholerae in Mozambique over time: Multilocus variable number tandem repeat analysis and whole genome sequencing.
Article in PLoS neglected tropical diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- A Fitness Burden Drives the Reversion of in vitro Acquired Doxycycline Resistance inInfection and drug resistance · 2026Article
- Genomic analysis and antimicrobial resistance ofMicrobial genomics · 2025Article
- Genomic insights into the 2022-2023Vibrio cholerae outbreak in Malawi.Nature communications · 2024Article
- Contrasting Epidemiology of Cholera in Bangladesh and Africa.The Journal of infectious diseases · 2021Review
- Population Analysis of Vibrio cholerae in Aquatic Reservoirs Reveals a Novel Sister Species (Applied and environmental microbiology · 2021Article
- Three transmission events of Vibrio cholerae O1 into Lusaka, Zambia.BMC infectious diseases · 2021Article
- A Vibrio cholerae Core Genome Multilocus Sequence Typing Scheme To Facilitate the Epidemiological Study of Cholera.Journal of bacteriology · 2020Article
- Genomic analysis of pathogenic isolates of Vibrio cholerae from eastern Democratic Republic of the Congo (2014-2017).PLoS neglected tropical diseases · 2020Article
- A molecular and epidemiological study of Vibrio cholerae isolates from cholera outbreaks in southern Ghana.PloS one · 2020Article
- Genomic insights into Vibrio cholerae O1 responsible for cholera epidemics in Tanzania between 1993 and 2017.PLoS neglected tropical diseases · 2019Article
- Mitigating Cholera in the Aftermath of Cyclone Idai.The American journal of tropical medicine and hygiene · 2019Article
- Comparative genomics for non-O1/O139 Vibrio cholerae isolates recovered from the Yangtze River Estuary versus V. cholerae representative isolates from serogroup O1.Molecular genetics and genomics : MGG · 2019Article
- Epidemiological and molecular forensics of cholera recurrence in Haiti.Scientific reports · 2019Article
- Surveillance and Genomics of ToxigenicFrontiers in microbiology · 2019Article
- Genetic relatedness of Vibrio cholerae isolates within and between households during outbreaks in Dhaka, Bangladesh.BMC genomics · 2017Article
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12 authors.
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Abstract
Although cholera is a major public health concern in Mozambique, its transmission patterns remain unknown. We surveyed the genetic relatedness of 75 Vibrio cholerae isolates from patients at Manhiça District Hospital between 2002-2012 and 3 isolates from river using multilocus variable-number tandem-repeat analysis (MLVA) and whole genome sequencing (WGS). MLVA revealed 22 genotypes in two clonal complexes and four unrelated genotypes. WGS revealed i) the presence of recombination, ii) 67 isolates descended monophyletically from a single source connected to Wave 3 of the Seventh Pandemic, and iii) four clinical isolates lacking the cholera toxin gene. This Wave 3 strain persisted for at least eight years in either an environmental reservoir or circulating within the human population. Our data raises important questions related to where these isolates persist and how identical isolates can be collected years apart despite our understanding of high change rate of MLVA loci and the V. cholerae molecular clock.
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