Evidence map›Paper›PMID 28622365›Full record

Trial reportPloS one2017

Association between socioeconomic deprivation and colorectal cancer screening outcomes: Low uptake rates among the most and least deprived people.

Andrea Buron, Josep M Auge, Maria Sala, Marta Román, Antoni Castells, Francesc Macià, Mercè Comas, Carolina Guiriguet, Xavier Bessa, Xavier Castells and 1 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
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  10. Factors Associated with Colorectal Cancer Screening in Spain: Results of the 2017 National Health Survey.International journal of environmental research and public health · 2022
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  16. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Andrea BuronEpidemiology and Evaluation Department, Hospital del Mar, Barcelona, Spain.ORCID http://orcid.org/0000-0003-3298-1125
Josep M AugeBiochemistry and Molecular Genetics Department, Hospital Clínic, Barcelona, Spain.
Maria SalaEpidemiology and Evaluation Department, Hospital del Mar, Barcelona, Spain.
Marta RománEpidemiology and Evaluation Department, Hospital del Mar, Barcelona, Spain.
Antoni CastellsIDIBAPS (August Pi i Sunyer Biomedical Research Institute), Barcelona, Spain.
Francesc MaciàEpidemiology and Evaluation Department, Hospital del Mar, Barcelona, Spain.
Mercè ComasEpidemiology and Evaluation Department, Hospital del Mar, Barcelona, Spain.
Carolina GuiriguetGòtic Primary Care Center, Catalan Institute of Health, Barcelona, Spain.
Xavier BessaIMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.
Xavier CastellsEpidemiology and Evaluation Department, Hospital del Mar, Barcelona, Spain.
and the PROCOLON research group
Spanish Clinical Research Network · ESHospital Clínic de Barcelona · ESInstitut Universitari d'Investigació en Atenció Primària Jordi Gol · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundScreening with faecal occult blood tests reduces colorectal cancer-related mortality; however, age, sex and socioeconomic factors affect screening outcomes and could lead to unequal mortality benefits. The aim of this study was to describe the main outcomes of the population-based Barcelona colorectal cancer screening programme (BCRCSP) by deprivation.

methodsRetrospective study of the eligible population of the first round of the BCRCSP. Participants' postal addresses were linked with the MEDEA database to obtain the deprivation quintiles (Dq). Chi-squared tests were used to compare proportions across variables and logistic regression was used to estimate the adjusted effects of age, sex and deprivation on uptake, FIT positivity, colonoscopy adherence and advanced neoplasia detection rate.

resultsOverall uptake was 44.7%, higher in Dq2, 3 and 4 (OR 1.251, 1.250 and 1.276, respectively) than in the least deprived quintile (Dq 1), and lowest in Dq5 (OR 0.84). Faecal immunochemical test (FIT) positivity and the percentage of people with detectable faecal haemoglobin below the positivity threshold increased with deprivation. The advanced neoplasia detection rate was highest in Dq4.

conclusionUnlike most regions where inequalities are graded along the socioeconomic continuum, inequalities in the uptake of colorectal cancer screening in Spain seem to be concentrated first in the most disadvantaged group and second in the least deprived group. The correlation of deprivation with FIT-positivity and faecal haemoglobin below the positivity threshold is worrying due to its association with colorectal cancer and overall mortality.

Indexed as

AgedColorectal NeoplasmsHumansMass ScreeningMiddle AgedRetrospective StudiesSocioeconomic FactorsSpain

Identifiers

PMID28622365
PMCPMC5473580
OpenAlexW2627015744

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.