Evidence map›Paper›PMID 28622313›Full record

ArticleEye (London, England)2017

Optical coherence tomography analysis of evolution of Bruch's membrane features in angioid streaks.

A Marchese, M Parravano, A Rabiolo, A Carnevali, E Corbelli, M V Cicinelli, M Battaglia Parodi, L Querques, F Bandello, G Querques

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Eye (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  6. Observational
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  9. Giant Idiopathic Angioid Streaks.Journal of ophthalmic & vision research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

A MarcheseDepartment of Ophthalmology, IRCCS Ospedale San Raffaele, University Vita-Salute, Milan, Italy.
M ParravanoG.B. Bietti Eye Foundation-IRCCS, Rome, Italy.
A RabioloDepartment of Ophthalmology, IRCCS Ospedale San Raffaele, University Vita-Salute, Milan, Italy.
A CarnevaliDepartment of Ophthalmology, IRCCS Ospedale San Raffaele, University Vita-Salute, Milan, Italy.
E CorbelliDepartment of Ophthalmology, IRCCS Ospedale San Raffaele, University Vita-Salute, Milan, Italy.
M V CicinelliDepartment of Ophthalmology, IRCCS Ospedale San Raffaele, University Vita-Salute, Milan, Italy.
M Battaglia ParodiDepartment of Ophthalmology, IRCCS Ospedale San Raffaele, University Vita-Salute, Milan, Italy.
L QuerquesDepartment of Ophthalmology, IRCCS Ospedale San Raffaele, University Vita-Salute, Milan, Italy.
F BandelloDepartment of Ophthalmology, IRCCS Ospedale San Raffaele, University Vita-Salute, Milan, Italy.
G QuerquesDepartment of Ophthalmology, IRCCS Ospedale San Raffaele, University Vita-Salute, Milan, Italy.
IRCCS Ospedale San Raffaele · ITFondazione G.B. Bietti · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PurposeTo describe optical coherence tomography (OCT) features in the Bruch's membrane (BM) of eyes with angioid streaks (AS) and evaluate their evolution over the follow-up.Patients and methodsPatients with AS presenting between March 2016 and September 2016 at two tertiary referral centers were consecutively recruited in this study. Eligibility criteria included prior spectral domain (SD)-OCT images, taken at least 3 months before at the same referral center, with automated eye tracking and image alignment modules. Alterations of BM were described and compared to previous scans over the follow-up. Multimodal imaging was used to identify alteration of retinal pigment epithelium (RPE) and choroid.ResultsThirty-two eyes of 16 consecutive patients with AS were included. BM undulations, mostly observed around the optic nerve head, were found in 19 (59.4%) of 32 eyes. BM breaks were found in 31 (96.9%) out of 32 eyes. Evolution of BM undulations into BM breaks was observed in 5 eyes (15.6%). Choroidal neovascularization (CNV) was observed in 12 eyes (37.5%) during follow-up, typically in areas of BM interruption.ConclusionsBM undulations, probably caused by high stretching forces exerted on the BM around the optic nerve head, seem to precede some BM breaks. BM interruptions may be a preferred way for the growth of CNV, which was identified in one-third of our cases.

Indexed as

Visual AcuityAgedAngioid StreaksBruch MembraneChoroidFemaleFluorescein AngiographyFollow-Up StudiesFundus OculiHumansMaleOptic DiskReproducibility of ResultsRetinal Pigment EpitheliumRetrospective StudiesTomography, Optical Coherence

Identifiers

PMID28622313
PMCPMC5684453
OpenAlexW2624998990

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.