Evidence map›Paper›PMID 28621492›Full record

ReviewJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2017

Tendons and Ligaments: Connecting Developmental Biology to Musculoskeletal Disease Pathogenesis.

Hiroshi Asahara, Masafumi Inui, Martin K Lotz

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05969145 (The Effect of Hot-Cold Application to the Bladder After Orthopedic Surgery on Postoperative Urinary Retention), which is not on this map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05969145 nacompletednot on this mapstarted 2023, after this paper: background citation

The Effect of Hot-Cold Application to the Bladder After Orthopedic Surgery on Postoperative Urinary Retention

TypeinterventionalSponsorAnkara Yildirim Beyazıt UniversityRan2023 to 2024Enrolled60ConditionsPostoperative Urinary RetentionArmsapplication of thermophor
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 107 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Fluoroquinolone-Mediated Tendinopathy and Tendon Rupture.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Biomineral-Based Composite Materials in Regenerative Medicine.International journal of molecular sciences · 2024
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Hiroshi AsaharaDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.
Masafumi InuiLaboratory of Animal Regeneration Systemology, Department of Life Science, School of Agriculture, Meiji University, Kanagawa, Japan.
Martin K LotzDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.
Kagawa University · JPScripps Research Institute · USTokyo Medical and Dental University · JP

Funding

TISSUE ACQUISITION, MORPHOLOGY, AND CELL CULTUREP01AG007996 · NIA · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI SAH, ROBERT L · 1989 to 2016
$26.0M
Transcriptional Regulation of ChondrogenesisR01AR050631 · NIAMS · SCRIPPS RESEARCH INSTITUTE, THE · PI ASAHARA, HIROSHI · 2004 to 2021
$5.8M
Transcription factor Mohawk in tendon and ligament degeneration and regenerationR01AR065379 · NIAMS · SCRIPPS RESEARCH INSTITUTE, THE · PI ASAHARA, HIROSHI · 2014 to 2018
$2.1M
The role of microRNAs in chondrogenesis and arthritisR56AR050631 · NIAMS · SCRIPPS RESEARCH INSTITUTE, THE · PI ASAHARA, HIROSHI · 2009 to 2009
$475k
NIAMS NIH HHS R01 AR050631NIAMS NIH HHS R01 AR065379NIAMS NIH HHS R56 AR050631NIA NIH HHS P01 AG007996
6 · The paper itself

Abstract

Tendons and ligaments provide connections between muscle and bone or bone and bone to enable locomotion. Damage to tendons and ligaments caused by acute or chronic injury or associated with aging and arthritis is a prevalent cause of disability. Improvements in approaches for the treatment of these conditions depend on a better understanding of tendon and ligament development, cell biology, and pathophysiology. This review focuses on recent advances in the discovery of transcription factors that control ligament and tendon cell differentiation, how cell and extracellular matrix homeostasis are altered in disease, and how this new insight can lead to novel therapeutic approaches. © 2017 American Society for Bone and Mineral Research.

Indexed as

AgingAnimalsArthritisExtracellular Matrix ProteinsHumansLigamentsTendon InjuriesTendonsTranscription FactorsExtracellular Matrix ProteinsTranscription FactorsARTHRITISEgr1/2LIGAMENTMkxScxTENDON

Identifiers

PMID28621492
PMCPMC5585011
OpenAlexW2626891185

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.