ReviewPaediatric drugs2017
Clinical Management of Dystonia in Childhood.
Review in Paediatric drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Botulinum Toxin in Children and Adolescents-A Comprehensive Review of Clinical Applications.Toxins · 2026Review
- Modeling cerebral palsy in animals.Developmental medicine and child neurology · 2026Review
- Deep brain stimulation for pediatric dystonia under general anesthesia with endotracheal intubation: case series in a tertiary hospital.Frontiers in pediatrics · 2026Article
- Family with BCL11B Related Dystonia and Movement Disorders.Movement disorders clinical practice · 2025Article
- Systemic Primary Carnitine Deficiency Presenting With Substantia Nigra and Basal Ganglia Injury: A Case Report.JIMD reports · 2025Article
- A low-cost, open-source device to evaluate limb stiffness in a rabbit model of cerebral palsy.Frontiers in bioengineering and biotechnology · 2025Article
- Clinical and Etiological Profile of Dystonia among Children.Indian journal of pediatrics · 2023Article
- Human equivalent doses of L-DOPA rescues retinal morphology and visual function in a murine model of albinism.Scientific reports · 2023Article
- Application of deep brain stimulation for the treatment of childhood-onset dystonia in patients with MEPAN syndrome.Frontiers in neurology · 2023Article
- Novel utilization of deep brain stimulation in the pedunculopontine nucleus with globus pallidus internus for treatment of childhood-onset dystonia.Frontiers in human neuroscience · 2023Article
- Hyperkinetic Movement Disorders in Children: A Brief Review.Iranian journal of child neurology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dystonia is one of the most frequent movement disorders in childhood. It can impede normal motor development and cause significant motor disability. The diagnostic evaluation of childhood dystonia is challenging due to the phenotypic variability and heterogeneous etiologies. Evidence to guide the diagnostic evaluation and treatment is limited. Assessment is primarily directed by clinical history and distinctive examination findings. Neuroimaging is typically necessary to evaluate for acquired or complex inherited dystonias. A trial of levodopa can be both diagnostic and therapeutic in children with dopa-responsive dystonia. However, for the majority of children with early-onset dystonia, treatment is symptomatic with varying efficacy. There is a paucity of therapeutic trials for childhood dystonia and most treatment recommendations are consensus or expert opinion driven. This review summarizes the available evidence and guidelines on the diagnostic evaluation and pharmacological treatment of childhood-onset dystonia and provides practical frameworks to approach both issues based on best evidence.
Indexed as
Identifiers
28620849What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.