Evidence map›Paper›PMID 28620797›Full record

ReviewHepatology international2017

Asia-Pacific clinical practice guidelines on the management of hepatocellular carcinoma: a 2017 update.

Masao Omata, Ann-Lii Cheng, Norihiro Kokudo, Masatoshi Kudo, Jeong Min Lee, Jidong Jia, Ryosuke Tateishi, Kwang-Hyub Han, Yoghesh K Chawla, Shuichiro Shiina and 11 more

4 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Hepatology international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 1,278 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,278citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04212273 naunknown statusnot on this mapstarted 2019, after this paper: background citation

A Single-center, Prospective Controlled Study of the Diagnostic Efficacies of Sonazoid-CEUS and EOB-MRI in Patients With High Risk of HCC

TypeinterventionalSponsorTianjin Third Central HospitalRan2019 to 2022Enrolled200ConditionsHepatocellular Cancer, Liver Cirrhoses, Diagnoses DiseaseArmsDiagnostic Sonazoid-CEUS and EOB-MRI
NCT05965388 not yet recruitingnot on this mapstarted 2023, after this paper: background citation

Predictive Value of HBV pgRNA on Long-term Outcomes in Hepatitis B Patients Treated With Antiviral Therapy

TypeobservationalSponsorWen-hong ZhangRan2023 to 2029Enrolled5,000ConditionsHBV, HCCArmsnucleoside analogues or interferon
NCT06096896 active not recruitingnot on this mapstarted 2023, after this paper: background citation

The Efficacy and Safety of EOB-MRI Guided Microwave Ablation for Early HCC: A Multicenter, Prospective, Observational Study

TypeobservationalSponsorShandong Provincial HospitalRan2023 to 2030Enrolled334ConditionsEarly Hepatocellular CarcinomaArmsMWA
NCT07319299 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

A Prospective, Interventional, Longitudinal APAC Study Evaluating Clinical Utility of GAAD Score for Detection of Hepatocellular Carcinoma in a High-risk APAC Patient Population

TypeinterventionalSponsorMahidol UniversityRan2025 to 2027Enrolled2,100ConditionsHepatecellular Carcinoma, Cirrhosis, HBV InfectionArmsGAAD score
3 · Its place in the literature

Who cites it

1,278 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Prevention, surveillance, and early detection of hepatocellular carcinoma - a Brazilian multidisciplinary consensus.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2026
    Guideline
  4. Guideline
  5. Guideline
  6. Guideline
  7. Pooled it
  8. Pooled it
  9. Guideline
  10. Pooled it
  11. Pooled it
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Article
  18. Review
  19. Article
  20. ALPS-HCC Score: A Dynamic Liver Stiffness Measurement-Based Machine Learning Model to Predict Risk of Hepatocellular Carcinoma.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article

1,218 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Masao OmataDepartment of Gastroenterology, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan. aug8808@yahoo.co.jp.
Ann-Lii ChengDepartment of Oncology and Internal Medicine, National Taiwan University Hospital, National Taiwan University Cancer Center and Graduate Institute of Oncology, National Taiwan University, Taipei, Taiwan.
Norihiro KokudoHepato-Biliary-Pancreatic Surgery Division and Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Masatoshi KudoDepartment of Gastroenterology and Hepatology, Kindai University School of Medicine, Osaka-Sayama, Osaka, Japan.
Jeong Min LeeDepartment of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Jidong JiaBeijing Key Laboratory of Translational Medicine on Cirrhosis, National Clinical Research Center for Digestive Diseases, Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Ryosuke TateishiDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Kwang-Hyub HanDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Yoghesh K ChawlaDepartment of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Shuichiro ShiinaDepartment of Gastroenterology, Juntendo University, Tokyo, Japan.
Wasim JafriDepartment of Medicine, Aga Khan University and Hospital, Karachi, Pakistan.
Diana Alcantara PayawalDepartment of Hepatology, Cardinal Santos Medical Center, Manila, Philippines.
Takamasa OhkiDepartment of Gastroenterology, Mitsui Memorial Hospital, Tokyo, Japan.
Sadahisa OgasawaraDepartment of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Pei-Jer ChenDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Cosmas Rinaldi A LesmanaDigestive Disease and GI Oncology Center, Medistra Hospital, University of Indonesia, Jakarta, Indonesia.
Laurentius A LesmanaDigestive Disease and GI Oncology Center, Medistra Hospital, University of Indonesia, Jakarta, Indonesia.
Rino A GaniDepartment of Internal Medicine, Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia.
Shuntaro ObiThird Department of Internal Medicine, Teikyo University School of Medicine, Chiba, Japan.
A Kadir DokmeciDepartment of Gastroenterology, Ankara University School of Medicine, Ankara, Turkey.
Shiv Kumar SarinDepartment of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is great geographical variation in the distribution of hepatocellular carcinoma (HCC), with the majority of all cases worldwide found in the Asia-Pacific region, where HCC is one of the leading public health problems. Since the "Toward Revision of the Asian Pacific Association for the Study of the Liver (APASL) HCC Guidelines" meeting held at the 25th annual conference of the APASL in Tokyo, the newest guidelines for the treatment of HCC published by the APASL has been discussed. This latest guidelines recommend evidence-based management of HCC and are considered suitable for universal use in the Asia-Pacific region, which has a diversity of medical environments.

Indexed as

AsiaCarcinoma, HepatocellularCoinfectionDisease ManagementEvidence-Based MedicineHepatitis BHepatitis CHumansLiver NeoplasmsMeta-Analysis as TopicPractice Guidelines as TopicAPASLAsia–PacificHepatocellular carcinomaTreatment algorithm

Identifiers

PMID28620797
PMCPMC5491694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.