SynthesisJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2017
Bundles Prevent Surgical Site Infections After Colorectal Surgery: Meta-analysis and Systematic Review.
Synthesis in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 7 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
62 citing papers in PubMed, 7 syntheses or guidelines pooled it, 183 citations in OpenAlex.
- Effect of negative pressure wound therapy on surgical wound outcomes in colorectal cancer surgery patients: a systematic review and meta-analysis.BMC surgery · 2026Pooled it
- Guidelines for Enhanced Recovery After Trauma and Intensive Care (ERATIC): Enhanced Recovery After Surgery (ERAS) and International Association for Trauma Surgery and Intensive Care (IATSIC) Society Recommendations: Paper 2: Postoperative and Intensive Care Recommendations.World journal of surgery · 2025Guideline
- Use of statistical process control in quality improvement projects in abdominal surgery: a PRISMA systematic review.BMJ open quality · 2024Pooled it
- Perioperative care bundles for the prevention of surgical-site infections: meta-analysis.The British journal of surgery · 2022Pooled it
- Pooled it
- Implementation interventions in preventing surgical site infections in abdominal surgery: a systematic review.BMC health services research · 2020Pooled it
- Effect of Subcutaneous Negative Suction Drain on Surgical Site Infection Following Colorectal Surgery: A Systematic Review and Meta-Analysis.ANZ journal of surgeryPooled it
- Comparison of two bundles for reducing surgical site infection in colorectal surgery: multicentre cohort study.BJS open · 2024Trial
- A postoperative body weight increase is a novel risk factor for incisional hernia of midline abdominal incision after elective gastroenterological surgery.Langenbeck's archives of surgery · 2023Trial
- Trial
- Article
- Implementation of an SSI care bundle for patients undergoing emergency laparotomy.Infection prevention in practice · 2026Article
- Seasonal trends in surgical site infections after hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- Surgical Approach as a Mediator of Rural-Urban Disparity after Colon Cancer Resection.Journal of the American College of Surgeons · 2026Article
- From Evidence to Implementation: A SIMPIOS Multimodal, Continuous Improvement Approach to Prevent Surgical Site Infections.Infection and drug resistance · 2026Review
- Long-Term Risk of Mesh Infection Requiring Removal After Elective Ventral Hernia Repair.JAMA surgery · 2025Article
- Beyond the Operating Room: A Narrative Review of Enhanced Recovery Strategies in Colorectal Surgery.Cureus · 2024Review
- The effect of damage control laparotomy on surgical-site infection risks after emergent intestinal surgery.Surgery · 2024Article
- You don't need to be a millionaire: pragmatic approach to implementing infection control and bowel recovery pathways in low resource environment.Surgical endoscopy · 2024Article
- Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionColorectal surgeries (CRS) have one of the highest rates of surgical site infections (SSIs) with rates 15 to >30%. Prevention "bundles" or sets of evidence-based interventions are structured ways to improve patient outcomes. The aim sof this study is to evaluate CRS SSI prevention bundles, bundle components, and implementation and compliance strategies.
methodsA meta-analysis of studies with pre- and post-implementation data was conducted to assess the impact of bundles on SSI rates (superficial, deep, and organ/space). Subgroup analysis of bundle components identified optimal bundle designs.
resultsThirty-five studies (51,413 patients) were identified and 23 (17,557 patients) were included in the meta-analysis. A SSI risk reduction of 40% (p < 0.001) was noted with 44% for superficial SSI (p < 0.001) and 34% for organ/space (p = 0.048). Bundles with sterile closure trays (58.6 vs 33.1%), MBP with oral antibiotics (55.4 vs 31.8%), and pre-closure glove changes (56.9 vs 28.5%) had significantly greater SSI risk reduction.
conclusionBundles can effectively reduce the risk of SSIs after CRS, by fostering a cohesive environment, standardization, and reduction in operative variance. If implemented successfully and complied with, bundles can become vital to improving patients' surgical quality of care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.