Evidence map›Paper›PMID 28620603›Full record

ReviewFrontiers in bioengineering and biotechnology2017

Advances in the Knowledge about Kidney Decellularization and Repopulation.

Afrânio Côgo Destefani, Gabriela Modenesi Sirtoli, Breno Valentim Nogueira

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  18. Extracellular Matrix in Kidney Fibrosis: More Than Just a Scaffold.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Afrânio Côgo DestefaniTissue Engineering Core-LUCCAR, Morphology, Federal University of Espírito Santo (UFES), Vitória, Brazil.
Gabriela Modenesi SirtoliTissue Engineering Core-LUCCAR, Morphology, Federal University of Espírito Santo (UFES), Vitória, Brazil.
Breno Valentim NogueiraTissue Engineering Core-LUCCAR, Morphology, Federal University of Espírito Santo (UFES), Vitória, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

End-stage renal disease (ESRD) is characterized by the progressive deterioration of renal function that may compromise different tissues and organs. The major treatment indicated for patients with ESRD is kidney transplantation. However, the shortage of available organs, as well as the high rate of organ rejection, supports the need for new therapies. Thus, the implementation of tissue bioengineering to organ regeneration has emerged as an alternative to traditional organ transplantation. Decellularization of organs with chemical, physical, and/or biological agents generates natural scaffolds, which can serve as basis for tissue reconstruction. The recellularization of these scaffolds with different cell sources, such as stem cells or adult differentiated cells, can provide an organ with functionality and no immune response after

Indexed as

bioengineeringdecellularizationkidney transplantationregenerative medicinestem cell

Identifiers

PMID28620603
PMCPMC5451511

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.