Evidence map›Paper›PMID 28620384›Full record

ArticleFrontiers in immunology2017

Measuring Leukocyte Adhesion to (Primary) Endothelial Cells after Photon and Charged Particle Exposure with a Dedicated Laminar Flow Chamber.

Nadine Erbeldinger, Felicitas Rapp, Svetlana Ktitareva, Philipp Wendel, Anna S Bothe, Till Dettmering, Marco Durante, Thomas Friedrich, Bianca Bertulat, Stephanie Meyer and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. A silicon nanomembrane platform for the visualization of immune cell trafficking across the human blood-brain barrier under flow.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
    Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Nadine ErbeldingerDepartment of Biophysics, GSI Helmholtz Center for Heavy Ion Research, Darmstadt, Germany.
Felicitas RappDepartment of Biophysics, GSI Helmholtz Center for Heavy Ion Research, Darmstadt, Germany.
Svetlana KtitarevaDepartment of Biophysics, GSI Helmholtz Center for Heavy Ion Research, Darmstadt, Germany.
Philipp WendelDepartment of Biophysics, GSI Helmholtz Center for Heavy Ion Research, Darmstadt, Germany.
Anna S BotheDepartment of Biophysics, GSI Helmholtz Center for Heavy Ion Research, Darmstadt, Germany.
Till DettmeringDepartment of Biophysics, GSI Helmholtz Center for Heavy Ion Research, Darmstadt, Germany.
Marco DuranteDepartment of Biophysics, GSI Helmholtz Center for Heavy Ion Research, Darmstadt, Germany.
Thomas FriedrichDepartment of Biophysics, GSI Helmholtz Center for Heavy Ion Research, Darmstadt, Germany.
Bianca BertulatDepartment of Biology, Technical University Darmstadt, Darmstadt, Germany.
Stephanie MeyerDepartment of Biology, Technical University Darmstadt, Darmstadt, Germany.
M C CardosoDepartment of Biology, Technical University Darmstadt, Darmstadt, Germany.
Stephanie HehlgansDepartment of Radiotherapy and Oncology, University of Frankfurt, Frankfurt, Germany.
Franz RödelDepartment of Radiotherapy and Oncology, University of Frankfurt, Frankfurt, Germany.
Claudia FournierDepartment of Biophysics, GSI Helmholtz Center for Heavy Ion Research, Darmstadt, Germany.
GSI Helmholtz Centre for Heavy Ion Research · DETechnical University of Darmstadt · DEGoethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vascular endothelium interacts with all types of blood cells and is a key modulator of local and systemic inflammatory processes, for example, in the adhesion of blood leukocytes to endothelial cells (EC) and the following extravasation into the injured tissue. The endothelium is constantly exposed to mechanical forces caused by blood flow, and the resulting shear stress is essential for the maintenance of endothelial function. Changes in local hemodynamics are sensed by EC, leading to acute or persistent changes. Therefore,

Indexed as

adhesionendothelial cellsimage analysisimage segmentationinflammation(particle) irradiationprimary lymphocytesshear stress

Identifiers

PMID28620384
PMCPMC5451490
OpenAlexW2617029543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.