Evidence map›Paper›PMID 28620319›Full record

ArticleFrontiers in physiology2017

Vascular Endothelial Growth Factor-B Induces a Distinct Electrophysiological Phenotype in Mouse Heart.

Nikolay Naumenko, Jenni Huusko, Tomi Tuomainen, Jussi T Koivumäki, Mari Merentie, Erika Gurzeler, Kari Alitalo, Riikka Kivelä, Seppo Ylä-Herttuala, Pasi Tavi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Nikolay NaumenkoA.I. Virtanen Institute for Molecular Sciences, University of Eastern FinlandKuopio, Finland.
Jenni HuuskoA.I. Virtanen Institute for Molecular Sciences, University of Eastern FinlandKuopio, Finland.
Tomi TuomainenA.I. Virtanen Institute for Molecular Sciences, University of Eastern FinlandKuopio, Finland.
Jussi T KoivumäkiA.I. Virtanen Institute for Molecular Sciences, University of Eastern FinlandKuopio, Finland.
Mari MerentieA.I. Virtanen Institute for Molecular Sciences, University of Eastern FinlandKuopio, Finland.
Erika GurzelerA.I. Virtanen Institute for Molecular Sciences, University of Eastern FinlandKuopio, Finland.
Kari AlitaloWihuri Research Institute and Translational Cancer Biology Program, University of Helsinki, Biomedicum HelsinkiHelsinki, Finland.
Riikka KiveläWihuri Research Institute and Translational Cancer Biology Program, University of Helsinki, Biomedicum HelsinkiHelsinki, Finland.
Seppo Ylä-HerttualaA.I. Virtanen Institute for Molecular Sciences, University of Eastern FinlandKuopio, Finland.
Pasi TaviA.I. Virtanen Institute for Molecular Sciences, University of Eastern FinlandKuopio, Finland.
University of Eastern Finland · FIUniversity of Helsinki · FIKuopio University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular endothelial growth factor B (VEGF-B) is a potent mediator of vascular, metabolic, growth, and stress responses in the heart, but the effects on cardiac muscle and cardiomyocyte function are not known. The purpose of this study was to assess the effects of VEGF-B on the energy metabolism, contractile, and electrophysiological properties of mouse cardiac muscle and cardiac muscle cells.

Indexed as

action potentialcardiac myocytesEC-couplingenergy metabolismgrowth factorsion channels

Identifiers

PMID28620319
PMCPMC5450225
OpenAlexW2617717350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.