Evidence map›Paper›PMID 28620198›Full record

ArticleScientific reports2017

Hydrogen gas protects IP3Rs by reducing disulfide bridges in human keratinocytes under oxidative stress.

Ching-Ying Wu, Wen-Li Hsu, Ming-Hsien Tsai, Jui-Lin Liang, Jian-He Lu, Chia-Jung Yen, Hsin-Su Yu, Mami Noda, Chi-Yu Lu, Chu-Huang Chen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Effects of Post-Treatment Hydrogen Gas Inhalation on Uveitis Induced by Endotoxin in Rats.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Ching-Ying WuDepartment of Dermatology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No. 68, Jhonghua 3rd Rd, Cianjin District, Kaohsiung, 80145, Taiwan.
Wen-Li HsuThe Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, 1 University Road, Tainan, 70101, Taiwan.
Ming-Hsien TsaiCenter for Lipid Biosciences, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Kaohsiung, 80708, Taiwan.
Jui-Lin LiangChi Mei Medical Center, No. 201, Taikang, Taikang Vil., Liuying Dist., Tainan City, 736, Taiwan.
Jian-He LuGraduate Institute of Medicine, School of Medicine, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Kaohsiung, 80708, Taiwan.
Chia-Jung YenCenter for Lipid Biosciences, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Kaohsiung, 80708, Taiwan.
Hsin-Su YuDepartment of Dermatology, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Kaohsiung, 80708, Taiwan.
Mami NodaLaboratory of Pathophysiology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1Maidashi, Higashi-ku, Fukuoka, 812-8581, Japan.
Chi-Yu LuDepartment of Biochemistry, College of Medicine, Kaohsiung Medical University, 100, Shih-Chuan 1st Road, Kaohsiung, 80708, Taiwan.
Chu-Huang ChenCenter for Lipid Biosciences, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Kaohsiung, 80708, Taiwan.
Shian-Jang YanThe Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, 1 University Road, Tainan, 70101, Taiwan. DROSOUV@gmail.com.
Tohru YoshiokaGraduate Institute of Medicine, School of Medicine, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Kaohsiung, 80708, Taiwan. yoshitohru@gmail.com.
Kaohsiung Medical University · TWKaohsiung Medical University Chung-Ho Memorial Hospital · TWChi Mei Medical Center · TWKyushu University · JPNational Cheng Kung University · TWNational Health Research Institutes · TWNew York Heart Research Foundation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Based on the oxidative stress theory, aging derives from the accumulation of oxidized proteins induced by reactive oxygen species (ROS) in the cytoplasm. Hydrogen peroxide (H

Indexed as

Adenosine TriphosphateCalciumCalcium SignalingCell Line, TumorChromatography, LiquidDisulfidesHumansHydrogenHydrogen PeroxideInositol 1,4,5-Trisphosphate ReceptorsKeratinocytesMass SpectrometryModels, AnatomicMolecular ImagingOxidative StressProtein ConformationAdenosine TriphosphateCalciumDisulfidesHydrogenHydrogen PeroxideInositol 1,4,5-Trisphosphate ReceptorsReactive Oxygen Species

Identifiers

PMID28620198
PMCPMC5472599
OpenAlexW2622116029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.