Evidence map›Paper›PMID 28620182›Full record

ArticleScientific reports2017

Residential radon exposure and brain cancer: an ecological study in a radon prone area (Galicia, Spain).

Alberto Ruano-Ravina, Nuria Aragonés, Karl T Kelsey, Mónica Pérez-Ríos, María Piñeiro-Lamas, Gonzalo López-Abente, Juan M Barros-Dios

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Radon Exposure and Neurodegenerative Disease.International journal of environmental research and public health · 2020
    Pooled it
  3. Review
  4. Article
  5. An overview on the relationship between residential radon and lung cancer: what we know and future research.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Review
  6. Cancer InFocus: Tools for Cancer Center Catchment Area Geographic Data Collection and Visualization.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
  7. Experimental Setups for In Vitro Studies on Radon Exposure in Mammalian Cells-A Critical Overview.International journal of environmental research and public health · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Residential Radon in Manizales, Colombia: Results of a Pilot Study.International journal of environmental research and public health · 2021
    Article
  15. Radon Exposure-Therapeutic Effect and Cancer Risk.International journal of molecular sciences · 2020
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alberto Ruano-RavinaDepartment of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago, Spain. alberto.ruano@usc.es.
Nuria AragonésCIBER de Epidemiología y Salud Pública, CIBERESP, Santiago, Spain.
Karl T KelseyDepartment of Epidemiology, Brown School of Public Health, Providence, Rhode, Island, USA.
Mónica Pérez-RíosDepartment of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago, Spain.
María Piñeiro-LamasCIBER de Epidemiología y Salud Pública, CIBERESP, Santiago, Spain.
Gonzalo López-AbenteCIBER de Epidemiología y Salud Pública, CIBERESP, Santiago, Spain.
Juan M Barros-DiosDepartment of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to know if radon concentration is associated with municipal mortality due to brain cancer in Galicia, Spain. We designed an ecological study taking as study unit Galician municipalities. To be included, municipalities had to have at least three radon measurements. We correlated radon concentrations with municipal mortality due to these malignant tumors during the period 1999-2008. We calculated the relative risk of dying of brain cancers for each municipality and correlated this value with municipal radon concentration using Spearman's Rho. 251 municipalities were included, with close to 3,500 radon measurements and an average of 14 radon measurements at each municipality. We observed a significant correlation between residential radon with brain cancer mortality for males and females and the intensity of the correlation was higher for females. These results were reinforced when the analysis was restricted to municipalities with more than 5 radon measurements: Spearman's Rho 0.286 (p-value < 0.001) and Spearman's Rho 0.509 (p-value < 0.001) for males and females, respectively. These results suggest an association between residential radon and brain cancer mortality. More research using more robust epidemiological designs is needed to confirm these findings.

Indexed as

Environmental ExposureAir Pollutants, RadioactiveBrain NeoplasmsCarcinogens, EnvironmentalFemaleHumansMaleRadonSex FactorsSpainSurvival AnalysisAir Pollutants, RadioactiveCarcinogens, EnvironmentalRadon

Identifiers

PMID28620182
PMCPMC5472649

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.